Early treatment with diltiazem reduces delayed cerebral vascular narrowing after subarachnoid hemorrhage

Using a primate model of subarachnoid hemorrhage, we have demonstrated the ability of diltiazem to reduce delayed, experimental narrowing of cerebral vessels under clinically realistic conditions. Twelve monkeys were treated identically, except that six received oral diltiazem (20 mg/kg t.i.d.) star...

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Veröffentlicht in:	Neurosurgery 1988-11, Vol.23 (5), p.611-615
Hauptverfasser:	FRAZEE, J. G, BEVAN, J. A, BEVAN, R. D, JONES, K. R, BIVENS, L. V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cardiovascular system Cerebrovascular Disorders - diagnostic imaging Cerebrovascular Disorders - drug therapy Cerebrovascular Disorders - etiology Diltiazem - therapeutic use Macaca nemestrina Medical sciences Pharmacology. Drug treatments Radiography Subarachnoid Hemorrhage - complications Subarachnoid Hemorrhage - drug therapy Vasodilator agents. Cerebral vasodilators
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