Genome Rearrangements Activate the Epstein-Barr Virus Gene Whose Product Disrupts Latency

A defective Epstein-Barr virus (EBV) containing a deleted and rearranged genome (het DNA) causes latent EBV to replicate. This activity maps to the 2.7-kilobase-pair WZhet fragment. The BZLF1 open reading frame, present within WZhet as well as in the standard viral BamHI Z fragment, encodes the prot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1988-12, Vol.85 (24), p.9801-9805
Hauptverfasser:	Rooney, C., Taylor, N., Countryman, J., Jenson, H., Kolman, J., Miller, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiserum B lymphocytes Base Sequence Biological and medical sciences Cell Line Cell lines Chromosome Deletion Deoxyribonuclease EcoRI - metabolism DNA Enhancer Elements, Genetic Epstein Barr virus infections Epstein-Barr virus Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genic rearrangement. Recombination. Transposable element Genomes Herpesvirus 4, Human - genetics Molecular and cellular biology Molecular genetics Palindromes Plasmids Promoter Regions, Genetic Simian virus 40 - genetics Transfection Viral Proteins - genetics Virus Replication Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!