Attenuation of Myocardial Stunning in Isolated Rat Hearts by a 21-Aminosteroid Lazaroid (U74389G)

SUMMARYThe purpose of this study was to evaluate the effects of reperfusion or in vivo pretreatment with a lipid peroxidation inhibitor, lazaroid (U74389G), on attenuating systolic and diastolic alterations occurring during myocardial stunning in isolated rat hearts. Male Sprague-Dawley rats (350-40...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1996-11, Vol.28 (5), p.659-664
Hauptverfasser:	Moreyra, Abel E, Conway, Robert S, Wilson, Alan C, Chen, Wen H, Schmidling, Michael J, Kostis, John B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use Biological and medical sciences Cardiovascular system Heart - drug effects Heart - physiopathology In Vitro Techniques Male Medical sciences Miscellaneous Myocardial Reperfusion Myocardial Stunning - prevention & control Pharmacology. Drug treatments Pregnatrienes - administration & dosage Pregnatrienes - therapeutic use Rats Rats, Sprague-Dawley Ventricular Pressure - drug effects
Online-Zugang:	Volltext
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