Prevention of high blood pressure by reducing sympathetic innervation in the spontaneously hypertensive rat

It has previously been reported that the increase in blood pressure in the spontaneously hypertensive rat (SHR) occurs concurrently with a marked increase in thickness of the arterial wall and an increase in vascular innervation, particularly for the small muscular arteries. The purpose of the prese...

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Veröffentlicht in:	Journal of the autonomic nervous system 1996-11, Vol.61 (2), p.97-102
Hauptverfasser:	Brock, James A., Van Helden, Dirk F., Dosen, Peter, Rush, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - pharmacology Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - physiology Cardiology. Vascular system Electrophysiology Experimental diseases Hyperinnervation Hypertension - physiopathology Hypertension - prevention & control Medical sciences Mesenteric Arteries - chemistry Mesenteric Arteries - innervation Mesenteric Arteries - physiopathology Mesenteric artery Nerve growth factor Nerve growth factor antibody Nerve Growth Factors - immunology Norepinephrine - metabolism Rats Rats, Inbred SHR Rats, Inbred WKY Sympathectomy Sympathetic Nervous System - physiology Vasoconstrictor Agents - metabolism
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