Effects of interferon-γ treatment on surgically simulated wound infection in mice

Interferon-γ (IFN-γ) has been shown to have immunoregulatory properties and is able to modulate resistance to several microbial infections. This study was designed to determine the efficacy of IFN-γ treatment in a mouse model of infection that simulates many clinical conditions associated with surgi...

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Veröffentlicht in:	Microbial pathogenesis 1988-02, Vol.4 (2), p.165-168
Hauptverfasser:	Hershman, Michael J., Sonnenfeld, Gerald, Mays, Bradley W., Fleming, Forrest, Trachtenberg, Laura S., Polk, Hiram C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - therapeutic use Animals Bacterial diseases Biological and medical sciences Experimental bacterial diseases and models Infectious diseases Interferon Interferon-gamma - therapeutic use Klebsiella Infections - drug therapy Klebsiella pneumoniae Male Medical sciences Mice Mice, Inbred CBA Space life sciences Surgical Wound Infection - therapy Sutures wound infection
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