Effects of bisphosphonate (pamidronate) on bone resorption resulting from metastasis of a squamous cell carcinoma: Report of an autopsy case and evaluation of bone resorbing activity in an experimental animal model

Purpose: This study evaluated the ability of bisphosphonate to prevent bone resorption induced by metastatic tumor cells. Materials and Methods: Autopsy specimens of a bone metastasis from a woman with a primary squamous cell carcinoma of the tongue who developed multiple osteolytic lesions and hype...

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