Inhibition of aminopeptidase A activity causes an acute albuminuria in mice: an angiotensin II-mediated effect?

The hydrolase aminopeptidase A is an important regulator of the renin-angiotensin system, since it inactivates its most vasoactive component angiotensin II (Ang II). A single i.v. injection of a monoclonal antibody against mouse aminopeptidase A (ASD-4) induces a membranous-like glomerulonephritis i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 1996-11, Vol.11 (11), p.2163-2169
Hauptverfasser:	Mentzel, S., Assmann, K. J. M., Dijkman, H. B. P. M., de Jong, A. S., van Son, J. P. H. F., Wetzels, J. F. M., Koene, R. A. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease albuminuria Albuminuria - etiology Albuminuria - metabolism aminopeptidase A Aminopeptidases - analysis Aminopeptidases - antagonists & inhibitors angiotensin II Angiotensin II - antagonists & inhibitors Angiotensin II - metabolism Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Biological and medical sciences Biphenyl Compounds - pharmacology Enalapril - pharmacology Glomerulonephritis Glutamyl Aminopeptidase Histocytochemistry Imidazoles - pharmacology In Situ Hybridization Losartan Medical sciences membranous glomerulonephritis Mice Mice, Inbred BALB C mouse Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure renin-angiotensin system Tetrazoles - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!