Melanotic neuroectodermal tumour of infancy (MNTI): immunohistochemical and ultrastructural study of a case
A case of melanotic neuroectodermal tumour of infancy (MNTI) which occurred in the left lower jaw of a 15-months old child was studied by electron microscopy and immunohistochemical methods to verify the neural crest origin of this tumour. Two cell population were observed: pigment melanocyte-like c...
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| Veröffentlicht in: | Journal of cranio-maxillo-facial surgery 1988-10, Vol.16 (7), p.330-336 |
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| container_end_page | 336 |
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| container_issue | 7 |
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| container_title | Journal of cranio-maxillo-facial surgery |
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| creator | MELISSARI, M TRAGNI, G GAETTI, L GABRIELLI, M BOZZETTI, A RAFFAINI, M |
| description | A case of melanotic neuroectodermal tumour of infancy (MNTI) which occurred in the left lower jaw of a 15-months old child was studied by electron microscopy and immunohistochemical methods to verify the neural crest origin of this tumour. Two cell population were observed: pigment melanocyte-like cells and non-pigmented nerve-like cells. Immunohistochemical analysis with neuron-specific enolase (NSE) and S-100 protein visualized two cell subtypes in the non-pigmented cell population. The combined ultrastructural findings and immunohistochemical data confirm the neural crest origin of MNTI. |
| doi_str_mv | 10.1016/s1010-5182(88)80073-8 |
| format | Article |
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Two cell population were observed: pigment melanocyte-like cells and non-pigmented nerve-like cells. Immunohistochemical analysis with neuron-specific enolase (NSE) and S-100 protein visualized two cell subtypes in the non-pigmented cell population. The combined ultrastructural findings and immunohistochemical data confirm the neural crest origin of MNTI.</description><identifier>ISSN: 1010-5182</identifier><identifier>EISSN: 1878-4119</identifier><identifier>DOI: 10.1016/s1010-5182(88)80073-8</identifier><identifier>PMID: 2848872</identifier><identifier>CODEN: JCMSET</identifier><language>eng</language><publisher>Kidlington: Elsevier</publisher><subject>Biological and medical sciences ; Cytoplasm - ultrastructure ; Cytoplasmic Granules - ultrastructure ; Dentistry ; Facial bones, jaws, teeth, parodontium: diseases, semeiology ; Humans ; Immunohistochemistry ; Infant ; Male ; Mandibular Neoplasms - pathology ; Mandibular Neoplasms - ultrastructure ; Medical sciences ; Melanocytes - ultrastructure ; Neoplasms, Germ Cell and Embryonal - pathology ; Neoplasms, Germ Cell and Embryonal - ultrastructure ; Otorhinolaryngology. 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Two cell population were observed: pigment melanocyte-like cells and non-pigmented nerve-like cells. Immunohistochemical analysis with neuron-specific enolase (NSE) and S-100 protein visualized two cell subtypes in the non-pigmented cell population. The combined ultrastructural findings and immunohistochemical data confirm the neural crest origin of MNTI.</description><subject>Biological and medical sciences</subject><subject>Cytoplasm - ultrastructure</subject><subject>Cytoplasmic Granules - ultrastructure</subject><subject>Dentistry</subject><subject>Facial bones, jaws, teeth, parodontium: diseases, semeiology</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Infant</subject><subject>Male</subject><subject>Mandibular Neoplasms - pathology</subject><subject>Mandibular Neoplasms - ultrastructure</subject><subject>Medical sciences</subject><subject>Melanocytes - ultrastructure</subject><subject>Neoplasms, Germ Cell and Embryonal - pathology</subject><subject>Neoplasms, Germ Cell and Embryonal - ultrastructure</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Tumors</subject><issn>1010-5182</issn><issn>1878-4119</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtPwzAQhC0EKlD4CZVyQKg9BOw4iTfcUMWjUguXco5sx1ZTkrj4cei_x4jAZXe182mkGYRmBN8RTMp7FydOCwLZHGABGDOawgm6IMAgzQmpTuP9h5yjS-f2GOMSQzVBkwxyAJZdoM-N6vhgfCuTQQVrlPSmUbbnXeJDb4JNjE7aQfNBHpP55m27Wjwkbd-Hwexa543cqb6VkeZDk4TOW-68DdIHG3_Oh-b4Y8ATyZ26Qmead05dj3uKPp6ftsvXdP3-slo-rtM9pdinAFqIhpSSN6zimjJVaiYU1qXUVOSVzrVQKiaQVBQNqRQhoigw4QQI0KKkU3T763uw5iso5-u-dVJ1MagywdUMirLMgERwNoJB9KqpD7btuT3WYztRvxl17mJGbWMLrfvHGMYFZEC_ASMidq0</recordid><startdate>19881001</startdate><enddate>19881001</enddate><creator>MELISSARI, M</creator><creator>TRAGNI, G</creator><creator>GAETTI, L</creator><creator>GABRIELLI, M</creator><creator>BOZZETTI, A</creator><creator>RAFFAINI, M</creator><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19881001</creationdate><title>Melanotic neuroectodermal tumour of infancy (MNTI): immunohistochemical and ultrastructural study of a case</title><author>MELISSARI, M ; TRAGNI, G ; GAETTI, L ; GABRIELLI, M ; BOZZETTI, A ; RAFFAINI, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j330t-88fbbd16cad79af37e6f7be0f6cf3b49f4fbee284c3b5d19e11b5501a18183563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Biological and medical sciences</topic><topic>Cytoplasm - ultrastructure</topic><topic>Cytoplasmic Granules - ultrastructure</topic><topic>Dentistry</topic><topic>Facial bones, jaws, teeth, parodontium: diseases, semeiology</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Infant</topic><topic>Male</topic><topic>Mandibular Neoplasms - pathology</topic><topic>Mandibular Neoplasms - ultrastructure</topic><topic>Medical sciences</topic><topic>Melanocytes - ultrastructure</topic><topic>Neoplasms, Germ Cell and Embryonal - pathology</topic><topic>Neoplasms, Germ Cell and Embryonal - ultrastructure</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MELISSARI, M</creatorcontrib><creatorcontrib>TRAGNI, G</creatorcontrib><creatorcontrib>GAETTI, L</creatorcontrib><creatorcontrib>GABRIELLI, M</creatorcontrib><creatorcontrib>BOZZETTI, A</creatorcontrib><creatorcontrib>RAFFAINI, M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cranio-maxillo-facial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MELISSARI, M</au><au>TRAGNI, G</au><au>GAETTI, L</au><au>GABRIELLI, M</au><au>BOZZETTI, A</au><au>RAFFAINI, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Melanotic neuroectodermal tumour of infancy (MNTI): immunohistochemical and ultrastructural study of a case</atitle><jtitle>Journal of cranio-maxillo-facial surgery</jtitle><addtitle>J Craniomaxillofac Surg</addtitle><date>1988-10-01</date><risdate>1988</risdate><volume>16</volume><issue>7</issue><spage>330</spage><epage>336</epage><pages>330-336</pages><issn>1010-5182</issn><eissn>1878-4119</eissn><coden>JCMSET</coden><abstract>A case of melanotic neuroectodermal tumour of infancy (MNTI) which occurred in the left lower jaw of a 15-months old child was studied by electron microscopy and immunohistochemical methods to verify the neural crest origin of this tumour. Two cell population were observed: pigment melanocyte-like cells and non-pigmented nerve-like cells. Immunohistochemical analysis with neuron-specific enolase (NSE) and S-100 protein visualized two cell subtypes in the non-pigmented cell population. The combined ultrastructural findings and immunohistochemical data confirm the neural crest origin of MNTI.</abstract><cop>Kidlington</cop><pub>Elsevier</pub><pmid>2848872</pmid><doi>10.1016/s1010-5182(88)80073-8</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of cranio-maxillo-facial surgery, 1988-10, Vol.16 (7), p.330-336 |
| issn | 1010-5182 1878-4119 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Biological and medical sciences Cytoplasm - ultrastructure Cytoplasmic Granules - ultrastructure Dentistry Facial bones, jaws, teeth, parodontium: diseases, semeiology Humans Immunohistochemistry Infant Male Mandibular Neoplasms - pathology Mandibular Neoplasms - ultrastructure Medical sciences Melanocytes - ultrastructure Neoplasms, Germ Cell and Embryonal - pathology Neoplasms, Germ Cell and Embryonal - ultrastructure Otorhinolaryngology. Stomatology Tumors |
| title | Melanotic neuroectodermal tumour of infancy (MNTI): immunohistochemical and ultrastructural study of a case |
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