MAOIs in Adolescent Major Depression Unresponsive to Tricyclic Antidepressants
Many adolescents with major depressive disorder have at most partial response to standard tricyclic antidepressants despite appropriate dosage and adequate length of treatment. This paper reports a series of 23 such adolescents who were treated with monoamine oxidase inhibitors (MAOIs). Seventy-four...
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| Veröffentlicht in: | Journal of the American Academy of Child and Adolescent Psychiatry 1988-11, Vol.27 (6), p.755-758 |
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| container_title | Journal of the American Academy of Child and Adolescent Psychiatry |
| container_volume | 27 |
| creator | RYAN, NEAL D. PUIG-ANTICH, JOAQUIM RABINOVICH, HARRIS FRIED, JANE AMBROSINI, PAUL MEYER, VIVECA TORRES, DEBORAH DACHILLE, SUSAN MAZZIE, DEBORAH |
| description | Many adolescents with major depressive disorder have at most partial response to standard tricyclic antidepressants despite appropriate dosage and adequate length of treatment. This paper reports a series of 23 such adolescents who were treated with monoamine oxidase inhibitors (MAOIs). Seventy-four percent of this group achieved good or fair antidepressant response, 57% had both good or fair response and continued dietary compliance. There were few serious side effects. Special attention must be paid to subject selection for treatment with MAOIs because of the risk of impulsive or accidental dietary transgression. This retrospective chart review strongly suggests the need for controlled studies of MAOI treatment in adolescents with tricyclic antidepressant refractory major depression. |
| doi_str_mv | 10.1097/00004583-198811000-00016 |
| format | Article |
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This paper reports a series of 23 such adolescents who were treated with monoamine oxidase inhibitors (MAOIs). Seventy-four percent of this group achieved good or fair antidepressant response, 57% had both good or fair response and continued dietary compliance. There were few serious side effects. Special attention must be paid to subject selection for treatment with MAOIs because of the risk of impulsive or accidental dietary transgression. This retrospective chart review strongly suggests the need for controlled studies of MAOI treatment in adolescents with tricyclic antidepressant refractory major depression.</description><identifier>ISSN: 0890-8567</identifier><identifier>EISSN: 1527-5418</identifier><identifier>DOI: 10.1097/00004583-198811000-00016</identifier><identifier>PMID: 3198564</identifier><identifier>CODEN: JAAPEE</identifier><language>eng</language><publisher>Hagerstown, MD: Elsevier Inc</publisher><subject>Adolescent ; adolescents ; Antidepressive Agents, Tricyclic - therapeutic use ; Biological and medical sciences ; Child ; Depressive Disorder - drug therapy ; Diet ; Female ; Humans ; major depression ; Male ; Medical sciences ; monoamine oxidase inhibitors ; Monoamine Oxidase Inhibitors - therapeutic use ; Neuropharmacology ; Patient Compliance ; Pharmacology. Drug treatments ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) ; Psychology. Psychoanalysis. Psychiatry ; Psychopharmacology ; tricyclic antidepressants</subject><ispartof>Journal of the American Academy of Child and Adolescent Psychiatry, 1988-11, Vol.27 (6), p.755-758</ispartof><rights>1988 The American Academy of Child and Adolescent Psychiatry</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c398t-40af1b1a3cc48db9c04259cde1fee84bd0a53416da956722a2c2bb37b48dd2193</citedby><cites>FETCH-LOGICAL-c398t-40af1b1a3cc48db9c04259cde1fee84bd0a53416da956722a2c2bb37b48dd2193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0890856709658597$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7119231$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3198564$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RYAN, NEAL D.</creatorcontrib><creatorcontrib>PUIG-ANTICH, JOAQUIM</creatorcontrib><creatorcontrib>RABINOVICH, HARRIS</creatorcontrib><creatorcontrib>FRIED, JANE</creatorcontrib><creatorcontrib>AMBROSINI, PAUL</creatorcontrib><creatorcontrib>MEYER, VIVECA</creatorcontrib><creatorcontrib>TORRES, DEBORAH</creatorcontrib><creatorcontrib>DACHILLE, SUSAN</creatorcontrib><creatorcontrib>MAZZIE, DEBORAH</creatorcontrib><title>MAOIs in Adolescent Major Depression Unresponsive to Tricyclic Antidepressants</title><title>Journal of the American Academy of Child and Adolescent Psychiatry</title><addtitle>J Am Acad Child Adolesc Psychiatry</addtitle><description>Many adolescents with major depressive disorder have at most partial response to standard tricyclic antidepressants despite appropriate dosage and adequate length of treatment. This paper reports a series of 23 such adolescents who were treated with monoamine oxidase inhibitors (MAOIs). Seventy-four percent of this group achieved good or fair antidepressant response, 57% had both good or fair response and continued dietary compliance. There were few serious side effects. Special attention must be paid to subject selection for treatment with MAOIs because of the risk of impulsive or accidental dietary transgression. This retrospective chart review strongly suggests the need for controlled studies of MAOI treatment in adolescents with tricyclic antidepressant refractory major depression.</description><subject>Adolescent</subject><subject>adolescents</subject><subject>Antidepressive Agents, Tricyclic - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Depressive Disorder - drug therapy</subject><subject>Diet</subject><subject>Female</subject><subject>Humans</subject><subject>major depression</subject><subject>Male</subject><subject>Medical sciences</subject><subject>monoamine oxidase inhibitors</subject><subject>Monoamine Oxidase Inhibitors - therapeutic use</subject><subject>Neuropharmacology</subject><subject>Patient Compliance</subject><subject>Pharmacology. Drug treatments</subject><subject>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopharmacology</subject><subject>tricyclic antidepressants</subject><issn>0890-8567</issn><issn>1527-5418</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOAyEUhonRaL08ggkL426UMwMdWNa7iZeNrgkDZxLMFCpMTfr2oq3dSkKAnO8_nHyEUGAXwFR7ycriQjYVKCkByqsqG6Y7ZAKibivBQe6SCZOKVVJM2wNymPPHD9JKuU_2m5ITUz4hL8-z18dMfaAzFwfMFsNIn81HTPQGFwlz9jHQ91Buixiy_0I6RvqWvF3ZwVs6C6N3a9CEMR-Tvd4MGU825xF5v7t9u36onl7vH69nT5VtlBwrzkwPHZjGWi5dpyzjtVDWIfSIkneOGdFwmDqjyvB1bWpbd13TdoV2NajmiJyv-y5S_FxiHvXcl9mHwQSMy6xbKYQSkhdQrkGbYs4Je71Ifm7SSgPTPyr1n0q9Val_VZbo6eaPZTdHtw1u3JX62aZusjVDn0ywPm-xFkDVDRTsao1h8fHlMelsPQaLzie0o3bR_z_LNyUGkDE</recordid><startdate>19881101</startdate><enddate>19881101</enddate><creator>RYAN, NEAL D.</creator><creator>PUIG-ANTICH, JOAQUIM</creator><creator>RABINOVICH, HARRIS</creator><creator>FRIED, JANE</creator><creator>AMBROSINI, PAUL</creator><creator>MEYER, VIVECA</creator><creator>TORRES, DEBORAH</creator><creator>DACHILLE, SUSAN</creator><creator>MAZZIE, DEBORAH</creator><general>Elsevier Inc</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19881101</creationdate><title>MAOIs in Adolescent Major Depression Unresponsive to Tricyclic Antidepressants</title><author>RYAN, NEAL D. ; PUIG-ANTICH, JOAQUIM ; RABINOVICH, HARRIS ; FRIED, JANE ; AMBROSINI, PAUL ; MEYER, VIVECA ; TORRES, DEBORAH ; DACHILLE, SUSAN ; MAZZIE, DEBORAH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c398t-40af1b1a3cc48db9c04259cde1fee84bd0a53416da956722a2c2bb37b48dd2193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adolescent</topic><topic>adolescents</topic><topic>Antidepressive Agents, Tricyclic - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Depressive Disorder - drug therapy</topic><topic>Diet</topic><topic>Female</topic><topic>Humans</topic><topic>major depression</topic><topic>Male</topic><topic>Medical sciences</topic><topic>monoamine oxidase inhibitors</topic><topic>Monoamine Oxidase Inhibitors - therapeutic use</topic><topic>Neuropharmacology</topic><topic>Patient Compliance</topic><topic>Pharmacology. Drug treatments</topic><topic>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopharmacology</topic><topic>tricyclic antidepressants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RYAN, NEAL D.</creatorcontrib><creatorcontrib>PUIG-ANTICH, JOAQUIM</creatorcontrib><creatorcontrib>RABINOVICH, HARRIS</creatorcontrib><creatorcontrib>FRIED, JANE</creatorcontrib><creatorcontrib>AMBROSINI, PAUL</creatorcontrib><creatorcontrib>MEYER, VIVECA</creatorcontrib><creatorcontrib>TORRES, DEBORAH</creatorcontrib><creatorcontrib>DACHILLE, SUSAN</creatorcontrib><creatorcontrib>MAZZIE, DEBORAH</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Child and Adolescent Psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RYAN, NEAL D.</au><au>PUIG-ANTICH, JOAQUIM</au><au>RABINOVICH, HARRIS</au><au>FRIED, JANE</au><au>AMBROSINI, PAUL</au><au>MEYER, VIVECA</au><au>TORRES, DEBORAH</au><au>DACHILLE, SUSAN</au><au>MAZZIE, DEBORAH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MAOIs in Adolescent Major Depression Unresponsive to Tricyclic Antidepressants</atitle><jtitle>Journal of the American Academy of Child and Adolescent Psychiatry</jtitle><addtitle>J Am Acad Child Adolesc Psychiatry</addtitle><date>1988-11-01</date><risdate>1988</risdate><volume>27</volume><issue>6</issue><spage>755</spage><epage>758</epage><pages>755-758</pages><issn>0890-8567</issn><eissn>1527-5418</eissn><coden>JAAPEE</coden><abstract>Many adolescents with major depressive disorder have at most partial response to standard tricyclic antidepressants despite appropriate dosage and adequate length of treatment. This paper reports a series of 23 such adolescents who were treated with monoamine oxidase inhibitors (MAOIs). Seventy-four percent of this group achieved good or fair antidepressant response, 57% had both good or fair response and continued dietary compliance. There were few serious side effects. Special attention must be paid to subject selection for treatment with MAOIs because of the risk of impulsive or accidental dietary transgression. This retrospective chart review strongly suggests the need for controlled studies of MAOI treatment in adolescents with tricyclic antidepressant refractory major depression.</abstract><cop>Hagerstown, MD</cop><pub>Elsevier Inc</pub><pmid>3198564</pmid><doi>10.1097/00004583-198811000-00016</doi><tpages>4</tpages></addata></record> |
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| subjects | Adolescent adolescents Antidepressive Agents, Tricyclic - therapeutic use Biological and medical sciences Child Depressive Disorder - drug therapy Diet Female Humans major depression Male Medical sciences monoamine oxidase inhibitors Monoamine Oxidase Inhibitors - therapeutic use Neuropharmacology Patient Compliance Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology tricyclic antidepressants |
| title | MAOIs in Adolescent Major Depression Unresponsive to Tricyclic Antidepressants |
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