Comparison of 17-Iodine-131 Heptadecanoic Acid Kinetics from Externally Measured Time-Activity Curves and from Serial Myocardial Biopsies in an Open-Chest Canine Model

The relation between the externally measured myocardial time-activity curve and the radiochemically determined kinetics of iodine-131(131I) heptadecanoic acid was studied in an open-chest canine model under different metabolic interventions. Kinetics were assessed by analysis of 12 biopsies taken in...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1988-12, Vol.29 (12), p.1934-1942
Hauptverfasser:	van Eenige, Machiel J, Visser, Frans C, Duwel, Caspar M.B, Karreman, Aart J.P, van Lingen, Arthur, Roos, Jan P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dipyridamole - pharmacology Dogs Fatty Acids - pharmacokinetics Glucose - pharmacology Heart - diagnostic imaging Heart - drug effects Iodine Radioisotopes Lactates - pharmacology Lactic Acid Myocardium - metabolism Norepinephrine - pharmacology Radionuclide Imaging
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