Direct evidence of cavitation in vivo from diagnostic ultrasound

Recent increases in the pressure output of diagnostic ultrasound scanners have led to an interest in establishing thresholds for bioeffects in many organs including the lungs of mammals. Damage may be mediated by inertial cavitation, yet there have been no such direct observations in vivo. To explor...

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Veröffentlicht in:Ultrasound in medicine & biology 1996, Vol.22 (7), p.917-925
Hauptverfasser: Holland, Christy K., Deng, Cheri X., Apfel, Robert E., Alderman, Jonathan L., Fernandez, Leonardo A., Taylor, Kenneth J.W.
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container_end_page 925
container_issue 7
container_start_page 917
container_title Ultrasound in medicine & biology
container_volume 22
creator Holland, Christy K.
Deng, Cheri X.
Apfel, Robert E.
Alderman, Jonathan L.
Fernandez, Leonardo A.
Taylor, Kenneth J.W.
description Recent increases in the pressure output of diagnostic ultrasound scanners have led to an interest in establishing thresholds for bioeffects in many organs including the lungs of mammals. Damage may be mediated by inertial cavitation, yet there have been no such direct observations in vivo. To explore the hypothesis of cavitation-based bioeffects from diagnostic ultrasound, research has been performed on the thresholds of damage in rat lungs exposed to 4.0-MHz pulsed Doppler and color Doppler ultrasound. A 30-MHz active cavitation detection scheme complementing these studies provides the first direct evidence of cavitation in vivo from diagnostic ultrasound pulses.
doi_str_mv 10.1016/0301-5629(96)00083-X
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Animals
Bioeffects
Biological and medical sciences
Cavitation
Color Doppler ultrasound
Diagnostic ultrasound
Doppler ultrasound
Extravasation of blood cells
Hemorrhage - etiology
Investigative techniques, diagnostic techniques (general aspects)
Lung - diagnostic imaging
Lung - pathology
Lung hemorrhage
Lung Injury
Medical sciences
Miscellaneous. Technology
Rat lung
Rats
Rats, Sprague-Dawley
Ultrasonic investigative techniques
Ultrasonography, Doppler, Color - adverse effects
Ultrasonography, Doppler, Pulsed - adverse effects
title Direct evidence of cavitation in vivo from diagnostic ultrasound
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