Atrial natriuretic peptide accelerates proliferation of chick embryonic cardiomyocytes in vitro

The developing embryonic heart has been reported to contain significant levels of atrial natriuretic peptide (ANP). In this study, the role of ANP in cardiac development was evaluated using cultured cardiomyocytes isolated from chick embryos. We analyzed the effect of ANP on cell number, DNA synthes...

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Veröffentlicht in:	Differentiation (London) 1996-10, Vol.61 (1), p.1-11
Hauptverfasser:	Koide, Masafumi, Akins, Robert E., Harayama, Hiroaki, Yasui, Kenji, Yokota, Mitsuhiro, Tuan, Rocky S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atrial Natriuretic Factor - pharmacology Atrial Natriuretic Factor - physiology Biological and medical sciences Cell Cycle Proteins - biosynthesis Cell Cycle Proteins - drug effects Cell Division - drug effects Cell physiology Cells, Cultured Chick Embryo Creatine Kinase - drug effects Creatine Kinase - metabolism DNA - biosynthesis DNA - drug effects Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental - drug effects Heart - drug effects Heart - embryology L-Lactate Dehydrogenase - drug effects L-Lactate Dehydrogenase - metabolism Molecular and cellular biology Myocardium - cytology Myocardium - metabolism Proteins - drug effects Responses to growth factors, tumor promotors, other factors RNA - drug effects Sarcomeres - chemistry Sarcomeres - drug effects Sarcomeres - metabolism
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