Mucosal melanotic macule, reactive type: A simulation of melanoma
Two patients with spontaneously resolving hyperpigmented patches of the oral mucosa are reported. Histologically, lesions in both cases showed large pigment-laden dendritic cells singly dispersed at all levels of the epidermis, which simulated in situ melanoma. The absence of such cells in the basal...
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| Veröffentlicht in: | Journal of the American Academy of Dermatology 1988-11, Vol.19 (5), p.786-791 |
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| container_issue | 5 |
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| container_title | Journal of the American Academy of Dermatology |
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| creator | Horlick, Howard P. Walther, Robert R. Zegarelli, David J. Silvers, David N. Eliezri, Yehuda D. |
| description | Two patients with spontaneously resolving hyperpigmented patches of the oral mucosa are reported. Histologically, lesions in both cases showed large pigment-laden dendritic cells singly dispersed at all levels of the epidermis, which simulated in situ melanoma. The absence of such cells in the basal layer of the epidermis served to histologically distinguish these lesions from a biologically malignant melanocyte tumor. Spontaneous resolution in both patients suggests that the condition is reactive. We propose the term
mucosal melanotic macule, reactive type, for this lesion, which has been described previously under the misnomer oral melanoacanthoma. |
| doi_str_mv | 10.1016/S0190-9622(88)70235-2 |
| format | Article |
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mucosal melanotic macule, reactive type, for this lesion, which has been described previously under the misnomer oral melanoacanthoma.</description><identifier>ISSN: 0190-9622</identifier><identifier>EISSN: 1097-6787</identifier><identifier>DOI: 10.1016/S0190-9622(88)70235-2</identifier><identifier>PMID: 3056992</identifier><identifier>CODEN: JAADDB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Diagnosis, Differential ; Epidermis - pathology ; Female ; Humans ; Male ; Medical sciences ; Melanocytes - pathology ; Melanoma - pathology ; Mouth Mucosa - pathology ; Non tumoral diseases ; Otorhinolaryngology. Stomatology ; Pigmentation Disorders - pathology ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><ispartof>Journal of the American Academy of Dermatology, 1988-11, Vol.19 (5), p.786-791</ispartof><rights>1988 American Academy of Dermatology, Inc.</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-c8011961f5938e4d7b51134c8526a09d8282d4f3d5bca0565bb729d7be30b0553</citedby><cites>FETCH-LOGICAL-c441t-c8011961f5938e4d7b51134c8526a09d8282d4f3d5bca0565bb729d7be30b0553</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0190-9622(88)70235-2$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7109529$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3056992$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Horlick, Howard P.</creatorcontrib><creatorcontrib>Walther, Robert R.</creatorcontrib><creatorcontrib>Zegarelli, David J.</creatorcontrib><creatorcontrib>Silvers, David N.</creatorcontrib><creatorcontrib>Eliezri, Yehuda D.</creatorcontrib><title>Mucosal melanotic macule, reactive type: A simulation of melanoma</title><title>Journal of the American Academy of Dermatology</title><addtitle>J Am Acad Dermatol</addtitle><description>Two patients with spontaneously resolving hyperpigmented patches of the oral mucosa are reported. Histologically, lesions in both cases showed large pigment-laden dendritic cells singly dispersed at all levels of the epidermis, which simulated in situ melanoma. The absence of such cells in the basal layer of the epidermis served to histologically distinguish these lesions from a biologically malignant melanocyte tumor. Spontaneous resolution in both patients suggests that the condition is reactive. We propose the term
mucosal melanotic macule, reactive type, for this lesion, which has been described previously under the misnomer oral melanoacanthoma.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Epidermis - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanocytes - pathology</subject><subject>Melanoma - pathology</subject><subject>Mouth Mucosa - pathology</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Pigmentation Disorders - pathology</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1LwzAUhoMoc05_wqAXIgpW89E0iTcyhl8w8UK9Dml6CpF2nUk72L8328puvToX53nPeXkQmhJ8RzDJ7z8xUThVOaXXUt4ITBlP6REaE6xEmgspjtH4gJyisxB-MMYqY2KERgzzXCk6RrP33rbB1EkDtVm2nbNJY2xfw23iwdjOrSHpNit4SGZJcE1fm861y6SthkBjztFJZeoAF8OcoO_np6_5a7r4eHmbzxapzTLSpVZiQlROKq6YhKwUBSeEZVZymhusSkklLbOKlbywJrbjRSGoihgwXGDO2QRd7e-ufPvbQ-h044KFOraAtg9aSM4UYSyCfA9a34bgodIr7xrjN5pgvVWnd-r01ouWUu_UaRpz0-FBXzRQHlKDq7i_HPYmWFNX3iytCwdMRPGcqog97jGIMtYOvA7WwdJC6TzYTpet-6fIH-m2iQE</recordid><startdate>19881101</startdate><enddate>19881101</enddate><creator>Horlick, Howard P.</creator><creator>Walther, Robert R.</creator><creator>Zegarelli, David J.</creator><creator>Silvers, David N.</creator><creator>Eliezri, Yehuda D.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19881101</creationdate><title>Mucosal melanotic macule, reactive type: A simulation of melanoma</title><author>Horlick, Howard P. ; Walther, Robert R. ; Zegarelli, David J. ; Silvers, David N. ; Eliezri, Yehuda D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-c8011961f5938e4d7b51134c8526a09d8282d4f3d5bca0565bb729d7be30b0553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Diagnosis, Differential</topic><topic>Epidermis - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Melanocytes - pathology</topic><topic>Melanoma - pathology</topic><topic>Mouth Mucosa - pathology</topic><topic>Non tumoral diseases</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Pigmentation Disorders - pathology</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Horlick, Howard P.</creatorcontrib><creatorcontrib>Walther, Robert R.</creatorcontrib><creatorcontrib>Zegarelli, David J.</creatorcontrib><creatorcontrib>Silvers, David N.</creatorcontrib><creatorcontrib>Eliezri, Yehuda D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Horlick, Howard P.</au><au>Walther, Robert R.</au><au>Zegarelli, David J.</au><au>Silvers, David N.</au><au>Eliezri, Yehuda D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mucosal melanotic macule, reactive type: A simulation of melanoma</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>1988-11-01</date><risdate>1988</risdate><volume>19</volume><issue>5</issue><spage>786</spage><epage>791</epage><pages>786-791</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Two patients with spontaneously resolving hyperpigmented patches of the oral mucosa are reported. Histologically, lesions in both cases showed large pigment-laden dendritic cells singly dispersed at all levels of the epidermis, which simulated in situ melanoma. The absence of such cells in the basal layer of the epidermis served to histologically distinguish these lesions from a biologically malignant melanocyte tumor. Spontaneous resolution in both patients suggests that the condition is reactive. We propose the term
mucosal melanotic macule, reactive type, for this lesion, which has been described previously under the misnomer oral melanoacanthoma.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>3056992</pmid><doi>10.1016/S0190-9622(88)70235-2</doi><tpages>6</tpages></addata></record> |
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| ispartof | Journal of the American Academy of Dermatology, 1988-11, Vol.19 (5), p.786-791 |
| issn | 0190-9622 1097-6787 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Adult Biological and medical sciences Diagnosis, Differential Epidermis - pathology Female Humans Male Medical sciences Melanocytes - pathology Melanoma - pathology Mouth Mucosa - pathology Non tumoral diseases Otorhinolaryngology. Stomatology Pigmentation Disorders - pathology Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
| title | Mucosal melanotic macule, reactive type: A simulation of melanoma |
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