A curved RNA helix incorporating an internal loop with G.A and A.A non-Watson-Crick base pairing

The crystal structure of the RNA dodecamer 5'-GGCC(GAAA)GGCC-3' has been determined from x-ray diffraction data to 2.3-A resolution. In the crystal, these oligomers form double helices around twofold symmetry axes. Four consecutive non-Watson-Crick base pairs make up an internal loop in th...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-11, Vol.93 (23), p.12851-12855
Hauptverfasser:	Baeyens, K J, De Bondt, H L, Pardi, A, Holbrook, S R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Base Composition Base Sequence Binding Sites Crystallography, X-Ray Guanine Hydrogen Bonding Metals Models, Genetic Models, Molecular Nucleic Acid Conformation Oligoribonucleotides - chemical synthesis Oligoribonucleotides - chemistry RNA - chemistry
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