Candida albicans arthritis one year after successful treatment of fungemia in a healthy infant

Fungal arthritis in pediatric patients is rare and is most often associated with hematogenous spread to the affected joint. It is generally seen concomitant with, or shortly after, fungemia. We report a case of an immunocompetent patient in whom candidal arthritis developed 1 year after initial fung...

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Veröffentlicht in:The Journal of pediatrics 1996-11, Vol.129 (5), p.688-694
Hauptverfasser: Swanson, Holly, Hughes, Patricia A., Messer, S.A., Lepow, M.L., Pfaller, Michael A.
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container_end_page 694
container_issue 5
container_start_page 688
container_title The Journal of pediatrics
container_volume 129
creator Swanson, Holly
Hughes, Patricia A.
Messer, S.A.
Lepow, M.L.
Pfaller, Michael A.
description Fungal arthritis in pediatric patients is rare and is most often associated with hematogenous spread to the affected joint. It is generally seen concomitant with, or shortly after, fungemia. We report a case of an immunocompetent patient in whom candidal arthritis developed 1 year after initial fungemia. The initial candidiasis was considered to be adequately treated with amphotericin B. The Candida isolates from the neonatal fungemia and subsequent arthritis were the same as identified by electrophoretic karyotype, restriction fragment length polymorphism analysis, and antifungal susceptibility testing. Pediatric candidal fungemia, arthritis, and their treatments are discussed.(J Pediatr 1996;129:688-94)
doi_str_mv 10.1016/S0022-3476(96)70151-8
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subjects Amphotericin B - therapeutic use
Antifungal Agents - therapeutic use
Arthritis, Infectious - microbiology
Biological and medical sciences
Candida albicans - isolation & purification
Female
Fungemia - complications
Fungemia - drug therapy
Fungemia - microbiology
Human mycoses
Humans
Infant, Newborn
Infectious diseases
Karyotyping
Medical sciences
Microbial Sensitivity Tests
Mycoses
Mycoses of the osteoarticular system
Polymorphism, Restriction Fragment Length
title Candida albicans arthritis one year after successful treatment of fungemia in a healthy infant
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