Acute effects of defibrotide, an experimental antithrombotic agent, on fibrinolysis and blood prostanoids in man

Defibrotide is a polynucleotide extracted from mammalian lung, which shows antithrombotic and anti-ischaemic activity in animals, probably related to stimulation of fibrinolysis and/or enhancement of prostacyclin production. The effect of a single infusion of defibrotide on fibrinolysis and the leve...

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Veröffentlicht in:	European journal of clinical pharmacology 1988-01, Vol.35 (2), p.151-156
Hauptverfasser:	COCCHERI, S, BIAGI, G, LEGNANI, C, BIANCHINI, B, GRAUSO, F
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Ketoprostaglandin F1 alpha - blood Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Dinoprostone - blood Double-Blind Method Female Fibrinolysis - drug effects Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - pharmacology Fibrinolytic Agents - therapeutic use Humans Infusions, Intravenous Male Medical sciences Pharmacology. Drug treatments Polydeoxyribonucleotides - administration & dosage Polydeoxyribonucleotides - pharmacology Polydeoxyribonucleotides - therapeutic use Random Allocation Thromboxane B2 - blood
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