Supraventricular Tachyarrhythmias After Coronary Bypass Surgery - A Double Blind Randomized Trial of Prophylactic Low Dose Propranolol
Summary In the present study 75 patients were double blind randomized either to receive 10 mg propranolol orally 4 times a day (35 patients) or a placebo (40 patients). Kpisodos of clinically important supra-ventricular tachyarrhythmias were recorded in the first 4 postoperative days. They appeared...
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| Veröffentlicht in: | The Thoracic and cardiovascular surgeon 1988-08, Vol.36 (4), p.206-207 |
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| container_end_page | 207 |
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| container_issue | 4 |
| container_start_page | 206 |
| container_title | The Thoracic and cardiovascular surgeon |
| container_volume | 36 |
| creator | Martinussen, H. J. Lolk, A. Szczepanski, C. Alstrup, P. |
| description | Summary
In the present study 75 patients were double blind randomized either to receive 10 mg propranolol orally 4 times a day (35 patients) or a placebo (40 patients). Kpisodos of clinically important supra-ventricular tachyarrhythmias were recorded in the first 4 postoperative days. They appeared in 5 of 35 patients receiving propranolol and in 5 of 40 patients receiving placebo (no statistically significant difference).
In conclusion this study indicates the need for further evaluation to clarify if low-dose propranolol or any other drug is effective in reducing the frequency of SVT in the early postoperative period after coronary artery bypass surgery. |
| doi_str_mv | 10.1055/s-2007-1020079 |
| format | Article |
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In the present study 75 patients were double blind randomized either to receive 10 mg propranolol orally 4 times a day (35 patients) or a placebo (40 patients). Kpisodos of clinically important supra-ventricular tachyarrhythmias were recorded in the first 4 postoperative days. They appeared in 5 of 35 patients receiving propranolol and in 5 of 40 patients receiving placebo (no statistically significant difference).
In conclusion this study indicates the need for further evaluation to clarify if low-dose propranolol or any other drug is effective in reducing the frequency of SVT in the early postoperative period after coronary artery bypass surgery.</description><identifier>ISSN: 0171-6425</identifier><identifier>EISSN: 1439-1902</identifier><identifier>DOI: 10.1055/s-2007-1020079</identifier><identifier>PMID: 2903581</identifier><language>eng</language><publisher>Germany</publisher><subject>Adrenergic beta-Antagonists - therapeutic use ; Clinical Trials as Topic ; Coronary Artery Bypass - adverse effects ; Double-Blind Method ; Drug Administration Schedule ; Humans ; Intraoperative Period ; Myocardial Infarction - complications ; Postoperative Period ; Propranolol - administration & dosage ; Propranolol - therapeutic use ; Random Allocation ; Tachycardia, Supraventricular - complications ; Tachycardia, Supraventricular - etiology ; Tachycardia, Supraventricular - prevention & control</subject><ispartof>The Thoracic and cardiovascular surgeon, 1988-08, Vol.36 (4), p.206-207</ispartof><rights>Georg Thieme Verlag Stuttgart · New York</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c328t-d01a927fea2195ae2d818dcf91bf529cbe670fb4c87f257d7d6532b067112aef3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-1020079.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,776,780,3004,3005,27901,27902,54534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2903581$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martinussen, H. J.</creatorcontrib><creatorcontrib>Lolk, A.</creatorcontrib><creatorcontrib>Szczepanski, C.</creatorcontrib><creatorcontrib>Alstrup, P.</creatorcontrib><title>Supraventricular Tachyarrhythmias After Coronary Bypass Surgery - A Double Blind Randomized Trial of Prophylactic Low Dose Propranolol</title><title>The Thoracic and cardiovascular surgeon</title><addtitle>Thorac cardiovasc Surg</addtitle><description>Summary
In the present study 75 patients were double blind randomized either to receive 10 mg propranolol orally 4 times a day (35 patients) or a placebo (40 patients). Kpisodos of clinically important supra-ventricular tachyarrhythmias were recorded in the first 4 postoperative days. They appeared in 5 of 35 patients receiving propranolol and in 5 of 40 patients receiving placebo (no statistically significant difference).
In conclusion this study indicates the need for further evaluation to clarify if low-dose propranolol or any other drug is effective in reducing the frequency of SVT in the early postoperative period after coronary artery bypass surgery.</description><subject>Adrenergic beta-Antagonists - therapeutic use</subject><subject>Clinical Trials as Topic</subject><subject>Coronary Artery Bypass - adverse effects</subject><subject>Double-Blind Method</subject><subject>Drug Administration Schedule</subject><subject>Humans</subject><subject>Intraoperative Period</subject><subject>Myocardial Infarction - complications</subject><subject>Postoperative Period</subject><subject>Propranolol - administration & dosage</subject><subject>Propranolol - therapeutic use</subject><subject>Random Allocation</subject><subject>Tachycardia, Supraventricular - complications</subject><subject>Tachycardia, Supraventricular - etiology</subject><subject>Tachycardia, Supraventricular - prevention & control</subject><issn>0171-6425</issn><issn>1439-1902</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UMuO0zAUtRBoKANbdkhesfNgO3UcLzsdXlIlEFPWlmNfE4-cONgJKHwA301KK3asju49D-kchF4yesOoEG8K4ZRKwugJ1CO0YdtKEaYof4w2lElG6i0XT9GzUh4oZdumUVfoiitaiYZt0O_7eczmBwxTDnaOJuOjsd1icu6WqeuDKXjnJ8h4n3IaTF7w7TKaUvD9nL_BehK8w3dpbiPg2xgGh7-YwaU-_AKHjzmYiJPHn3MauyUaOwWLD-nn6ijw95vNkGKKz9ETb2KBFxe8Rl_fvT3uP5DDp_cf97sDsRVvJuIoM4pLD4YzJQxw17DGWa9Y6wVXtoVaUt9ubSM9F9JJV4uKt7SWjHEDvrpGr8-5Y07fZyiT7kOxEKMZIM1Fy0bwilX1Krw5C21OpWTwesyhX_trRvVpeF30aXF9GX41vLokz20P7p_8svTKkzM_dQF60A9pzsNa9X95fwBcPY5b</recordid><startdate>19880801</startdate><enddate>19880801</enddate><creator>Martinussen, H. J.</creator><creator>Lolk, A.</creator><creator>Szczepanski, C.</creator><creator>Alstrup, P.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19880801</creationdate><title>Supraventricular Tachyarrhythmias After Coronary Bypass Surgery - A Double Blind Randomized Trial of Prophylactic Low Dose Propranolol</title><author>Martinussen, H. J. ; Lolk, A. ; Szczepanski, C. ; Alstrup, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c328t-d01a927fea2195ae2d818dcf91bf529cbe670fb4c87f257d7d6532b067112aef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adrenergic beta-Antagonists - therapeutic use</topic><topic>Clinical Trials as Topic</topic><topic>Coronary Artery Bypass - adverse effects</topic><topic>Double-Blind Method</topic><topic>Drug Administration Schedule</topic><topic>Humans</topic><topic>Intraoperative Period</topic><topic>Myocardial Infarction - complications</topic><topic>Postoperative Period</topic><topic>Propranolol - administration & dosage</topic><topic>Propranolol - therapeutic use</topic><topic>Random Allocation</topic><topic>Tachycardia, Supraventricular - complications</topic><topic>Tachycardia, Supraventricular - etiology</topic><topic>Tachycardia, Supraventricular - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martinussen, H. J.</creatorcontrib><creatorcontrib>Lolk, A.</creatorcontrib><creatorcontrib>Szczepanski, C.</creatorcontrib><creatorcontrib>Alstrup, P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Thoracic and cardiovascular surgeon</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martinussen, H. J.</au><au>Lolk, A.</au><au>Szczepanski, C.</au><au>Alstrup, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Supraventricular Tachyarrhythmias After Coronary Bypass Surgery - A Double Blind Randomized Trial of Prophylactic Low Dose Propranolol</atitle><jtitle>The Thoracic and cardiovascular surgeon</jtitle><addtitle>Thorac cardiovasc Surg</addtitle><date>1988-08-01</date><risdate>1988</risdate><volume>36</volume><issue>4</issue><spage>206</spage><epage>207</epage><pages>206-207</pages><issn>0171-6425</issn><eissn>1439-1902</eissn><abstract>Summary
In the present study 75 patients were double blind randomized either to receive 10 mg propranolol orally 4 times a day (35 patients) or a placebo (40 patients). Kpisodos of clinically important supra-ventricular tachyarrhythmias were recorded in the first 4 postoperative days. They appeared in 5 of 35 patients receiving propranolol and in 5 of 40 patients receiving placebo (no statistically significant difference).
In conclusion this study indicates the need for further evaluation to clarify if low-dose propranolol or any other drug is effective in reducing the frequency of SVT in the early postoperative period after coronary artery bypass surgery.</abstract><cop>Germany</cop><pmid>2903581</pmid><doi>10.1055/s-2007-1020079</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0171-6425 |
| ispartof | The Thoracic and cardiovascular surgeon, 1988-08, Vol.36 (4), p.206-207 |
| issn | 0171-6425 1439-1902 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78523136 |
| source | MEDLINE; Thieme Connect Journals |
| subjects | Adrenergic beta-Antagonists - therapeutic use Clinical Trials as Topic Coronary Artery Bypass - adverse effects Double-Blind Method Drug Administration Schedule Humans Intraoperative Period Myocardial Infarction - complications Postoperative Period Propranolol - administration & dosage Propranolol - therapeutic use Random Allocation Tachycardia, Supraventricular - complications Tachycardia, Supraventricular - etiology Tachycardia, Supraventricular - prevention & control |
| title | Supraventricular Tachyarrhythmias After Coronary Bypass Surgery - A Double Blind Randomized Trial of Prophylactic Low Dose Propranolol |
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