Analysis of the expression directed by two HTLV-I promoters in transgenic mice

We generated several lines of mice transgenic for the lacZ reporter gene under the control of an HTLV-I LTR. Two different LTR were used; one was isolated from a case of Adult T-cell Leukemia (ATL), the other from a case of Tropical Spastic Paraparesis (TSP/HAM). These LTR differed at 18 nucleotide...

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Veröffentlicht in:	Journal of neurovirology 1996-10, Vol.2 (5), p.336-344
Hauptverfasser:	Coscoy, Laurent, Gonzalez-dunia, Daniel, Chirinian-syan, Sylvie, Brahic, Michel, Ozden, Simona
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Astrocytes - physiology Astrocytes - virology beta-Galactosidase Brain - cytology DNA Methylation DNA, Viral - analysis Gene Expression - genetics Genes, Reporter Human T-lymphotropic virus 1 - genetics Humans Immunoenzyme Techniques In Situ Hybridization Mice Mice, Transgenic Paraparesis, Tropical Spastic - virology Point Mutation Promoter Regions, Genetic - genetics Transgenes
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