The absence of any pre-emptive analgesic effect for non-steroidal anti-inflammatory drugs
Pre-emptive analgesic efficacy of the non-steroidal anti-inflammatory drug, diclofenac sodium, was tested in 21 young, fit, patients undergoing third molar extractions in a double-blind, randomised, cross-over, trial. Pain scores and mouth opening were observed for 1 week after the operation and the...
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| Veröffentlicht in: | British journal of oral & maxillofacial surgery 1996-10, Vol.34 (5), p.428-431 |
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| container_issue | 5 |
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| container_title | British journal of oral & maxillofacial surgery |
| container_volume | 34 |
| creator | Bridgman, J.B. Gillgrass, T.G. Zacharias, M. |
| description | Pre-emptive analgesic efficacy of the non-steroidal anti-inflammatory drug, diclofenac sodium, was tested in 21 young, fit, patients undergoing third molar extractions in a double-blind, randomised, cross-over, trial. Pain scores and mouth opening were observed for 1 week after the operation and these did not show any differences following pre- and postoperative oral administration of diclofenac sodium 100 mg (
P > 0.05). There were no differences in the patients' preference for the two methods of treatment (
P > 0.05). The study suggests that the non-steroidal anti-inflammatory drug diclofenac sodium does not cause any significant pre-emptive analgesic effects in the dose administered. |
| doi_str_mv | 10.1016/S0266-4356(96)90101-1 |
| format | Article |
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P > 0.05). There were no differences in the patients' preference for the two methods of treatment (
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P > 0.05). There were no differences in the patients' preference for the two methods of treatment (
P > 0.05). The study suggests that the non-steroidal anti-inflammatory drug diclofenac sodium does not cause any significant pre-emptive analgesic effects in the dose administered.</description><subject>Adult</subject><subject>Analgesia</subject><subject>Analysis of Variance</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cross-Over Studies</subject><subject>Dentistry</subject><subject>Diclofenac - therapeutic use</subject><subject>Double-Blind Method</subject><subject>Ent. Stomatology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - etiology</subject><subject>Pain, Postoperative - prevention & control</subject><subject>Pharmacology. Drug treatments</subject><subject>Tooth Extraction - adverse effects</subject><issn>0266-4356</issn><issn>1532-1940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1rGzEQhkVoSJ2Pn2DYQynNQak-rI89lWKSthDIIckhJyFLI1dld-VKa4P_fbWx8bUwMDDvMyPxIDSn5I4SKr8-EyYlXnAhv7TytiV1iOkZmlHBGabtgnxAsxPyEV2W8ocQIhgVF-hCt6RVXM7Q28tvaOyqwOCgSaGxw77ZZMDQb8a4q9FguzWU6BoIAdzYhJSbIQ24jJBT9LaryBhxHEJn-96OKe8bn7frco3Og-0K3Bz7FXp9uH9Z_sSPTz9-Lb8_Ysd1O2KpBZMr74VgghEtuebOARNqxZmXgTiqLAjbWmUd0UIR70EH5TVjTFAV-BX6fLi7yenvFspo-lgcdJ0dIG2LUVpQSYWuoDiALqdSMgSzybG3eW8oMZNS867UTL5MW2tSamjdmx8f2K568Keto8OafzrmtjjbhWwHF8sJYwvFOZ2wbwcMqoxdhGyKi5N2H3MVa3yK__nIP5CJkrA</recordid><startdate>19961001</startdate><enddate>19961001</enddate><creator>Bridgman, J.B.</creator><creator>Gillgrass, T.G.</creator><creator>Zacharias, M.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19961001</creationdate><title>The absence of any pre-emptive analgesic effect for non-steroidal anti-inflammatory drugs</title><author>Bridgman, J.B. ; Gillgrass, T.G. ; Zacharias, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-68526bdd55252086383cce257b32d6f0c17ae5a9a7ac08570dde8f7d8222517f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Analgesia</topic><topic>Analysis of Variance</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cross-Over Studies</topic><topic>Dentistry</topic><topic>Diclofenac - therapeutic use</topic><topic>Double-Blind Method</topic><topic>Ent. Stomatology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - etiology</topic><topic>Pain, Postoperative - prevention & control</topic><topic>Pharmacology. Drug treatments</topic><topic>Tooth Extraction - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bridgman, J.B.</creatorcontrib><creatorcontrib>Gillgrass, T.G.</creatorcontrib><creatorcontrib>Zacharias, M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of oral & maxillofacial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bridgman, J.B.</au><au>Gillgrass, T.G.</au><au>Zacharias, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The absence of any pre-emptive analgesic effect for non-steroidal anti-inflammatory drugs</atitle><jtitle>British journal of oral & maxillofacial surgery</jtitle><addtitle>Br J Oral Maxillofac Surg</addtitle><date>1996-10-01</date><risdate>1996</risdate><volume>34</volume><issue>5</issue><spage>428</spage><epage>431</epage><pages>428-431</pages><issn>0266-4356</issn><eissn>1532-1940</eissn><coden>BJOSEY</coden><abstract>Pre-emptive analgesic efficacy of the non-steroidal anti-inflammatory drug, diclofenac sodium, was tested in 21 young, fit, patients undergoing third molar extractions in a double-blind, randomised, cross-over, trial. Pain scores and mouth opening were observed for 1 week after the operation and these did not show any differences following pre- and postoperative oral administration of diclofenac sodium 100 mg (
P > 0.05). There were no differences in the patients' preference for the two methods of treatment (
P > 0.05). The study suggests that the non-steroidal anti-inflammatory drug diclofenac sodium does not cause any significant pre-emptive analgesic effects in the dose administered.</abstract><cop>Londonc</cop><pub>Elsevier Ltd</pub><pmid>8909736</pmid><doi>10.1016/S0266-4356(96)90101-1</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0266-4356 |
| ispartof | British journal of oral & maxillofacial surgery, 1996-10, Vol.34 (5), p.428-431 |
| issn | 0266-4356 1532-1940 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Analgesia Analysis of Variance Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Biological and medical sciences Cross-Over Studies Dentistry Diclofenac - therapeutic use Double-Blind Method Ent. Stomatology Female Humans Male Medical sciences Pain Measurement Pain, Postoperative - etiology Pain, Postoperative - prevention & control Pharmacology. Drug treatments Tooth Extraction - adverse effects |
| title | The absence of any pre-emptive analgesic effect for non-steroidal anti-inflammatory drugs |
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