The outcome of the parasitic process initiated by Leishmania infantum in laboratory mice: a tissue-dependent pattern controlled by the Lsh and MHC loci

Human visceral leishmaniasis is mainly due to intracellular protozoan parasites of the Leishmania donovani complex, i.e., L. donovani and L. infantum (or L. chagasi). A mouse model has been established to monitor 1) the parasitic process initiated by L. infantum in three tissues they invade, and 2)...

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Veröffentlicht in:	The Journal of immunology (1950) 1996-11, Vol.157 (10), p.4537-4545
Hauptverfasser:	Leclercq, V, Lebastard, M, Belkaid, Y, Louis, J, Milon, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Carrier Proteins - genetics Carrier Proteins - immunology Cation Transport Proteins Female Iron-Binding Proteins Leishmania infantum Leishmania infantum - immunology Leishmaniasis, Visceral - etiology Leishmaniasis, Visceral - genetics Leishmaniasis, Visceral - parasitology Liver Diseases, Parasitic - parasitology Major Histocompatibility Complex - genetics Major Histocompatibility Complex - immunology Membrane Proteins - genetics Membrane Proteins - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Organ Specificity - genetics Organ Specificity - immunology Splenic Diseases - parasitology
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