Comparison of the Vbeta repertoire in peripheral blood and in lymph nodes of HIV-infected subjects reveals skewed usage predominantly in CD8+ T cells

Perturbations of the repertoire of variable-beta (Vbeta) regions of the T cell receptor have been observed in patients infected by HIV and have been attributed to stimulation by viral antigens or superantigens. We further sought for traces of HIV-induced perturbations by comparing Vbeta repertoire i...

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Veröffentlicht in:	Clinical immunology and immunopathology 1996-11, Vol.81 (2), p.200-209
Hauptverfasser:	Carbonari, M, Cibati, M, Pesce, A M, Dell'Anna, L, D'Offizi, G, Angelici, A, Uccini, S, Fiorilli, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV CD4-Positive T-Lymphocytes - chemistry CD8-Positive T-Lymphocytes - chemistry Female Flow Cytometry HIV Infections - blood HIV Infections - metabolism Humans Immunoglobulin Variable Region - blood Immunohistochemistry Lymph Nodes - chemistry Lymphocyte Activation Male Receptors, Antigen, T-Cell, alpha-beta - blood T-Lymphocytes - immunology
Online-Zugang:	Volltext
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