Antioxidant properties of hydroxy-flavones

The antioxidant properties of 24 hydroxy-flavones were evaluated. Results show that 2′,3′,4′-OH substitution on the B ring plays a crucial role in radical scavenger activity in the DPPH assay and in the inhibitory effect on pereoxydation of tissue lipids in the MDA test. The formation of stable radi...

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Veröffentlicht in:	Free radical biology & medicine 1996, Vol.20 (1), p.35-43
Hauptverfasser:	Cotelle, Nicole, Bernier, Jean-Luc, Catteau, Jean-Pierre, Pommery, Jean, Wallet, Jean-Claude, Gaydou, Emile M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Antioxidants - pharmacology Benzoquinones - chemistry Benzoquinones - metabolism Bepridil - analogs & derivatives Bepridil - metabolism Binding Sites Biphenyl Compounds Electron Spin Resonance Spectroscopy ESR Flavones Flavonoids - chemistry Flavonoids - metabolism Flavonoids - pharmacology Free Radical Scavengers - metabolism Free Radical Scavengers - pharmacology Free radicals Free Radicals - metabolism Kinetics Lipid Peroxidation - drug effects Luminescent Measurements Molecular Structure Picrates Radical scavengers Spectrophotometry, Ultraviolet Thiobarbituric Acid Reactive Substances Xanthine Oxidase - antagonists & inhibitors Xanthine Oxidase - metabolism Xanthine oxidase inhibitors
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