Endothelin release is augmented with captopril in rat ischemia-reperfusion injury of the liver

The reactive oxygen metabolites (ROMs) and the vascular endothelial factors such as endothelins (ETs) and thromboxane A2 (TxA2) were found to be mediators of the reperfusion component of ischemia-reperfusion (I/R) injury. Captopril (CPT), a sulfydryl (-SH) group containing angiotensin-converting enz...

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Veröffentlicht in:	Research in experimental medicine 1996, Vol.196 (4), p.227-233
Hauptverfasser:	Güllüoğlu, B M, Aktan, A O, Yeğen, C, Kurtel, H, Yalin, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Captopril - pharmacology Dinoprostone - blood Endothelin-1 - blood Endothelin-1 - metabolism Free Radical Scavengers - metabolism Leukotriene C4 - blood Liver - metabolism Male Rats Rats, Wistar Reactive Oxygen Species - metabolism Reperfusion Injury - metabolism Vasodilator Agents - pharmacology
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