Pitfalls in the evaluation of isometric strength (TQNE) data in ALS
The phase of rapid reduction of isometric strength in single muscle groups was identified and its slope was calculated in patients studied with the TQNE method. This parameter was studied in the extremities and in respiration in 4 ALS patients and 4 PMA (progressive spinal muscle atrophy) patients....
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| Veröffentlicht in: | Journal of the neurological sciences 1996-08, Vol.139 (suppl), p.60-63 |
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| container_end_page | 63 |
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| container_issue | suppl |
| container_start_page | 60 |
| container_title | Journal of the neurological sciences |
| container_volume | 139 |
| creator | Conradi, Sebastian Ronnevi, Lars-Olof |
| description | The phase of rapid reduction of isometric strength in single muscle groups was identified and its slope was calculated in patients studied with the TQNE method. This parameter was studied in the extremities and in respiration in 4 ALS patients and 4 PMA (progressive spinal muscle atrophy) patients. The slopes of the strength reduction in these muscle groups and their mean values exceeded the slopes of the corresponding megascores; this difference was larger in the extremities than in respiration. It is concluded that repeated spirometry gives a good expression of reduction of muscle strength in ALS, and is well suited for monitoring treatment effects. |
| doi_str_mv | 10.1016/0022-510X(96)00121-9 |
| format | Article |
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Prion diseases</subject><subject>Disease Progression</subject><subject>Electromyography - standards</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Humans</subject><subject>Isometric Contraction - physiology</subject><subject>Isometric strength</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscular Atrophy, Spinal - physiopathology</subject><subject>Neurology</subject><subject>Neuromuscular disease</subject><subject>Regression Analysis</subject><subject>Respiration</subject><subject>Respiratory Function Tests</subject><issn>0022-510X</issn><issn>1878-5883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkNFKHDEUhkOp6Nb2DRTmoohejD3JJJnkprAsthUW26KCdyGbOaOR2ZltkhF8-2bYZS_15oRwvv_n8BFyQuGSApXfABgrBYWHcy0vACijpf5AZlTVqhRKVR_JbI8ckU8xPgOAVEofksM8tZQwI4s_PrW262Lh-yI9YYEvthtt8kNfDG3h47DGFLwrYgrYP6an4vzu783VRdHYZKfMfHn7mRzkiohfdu8xuf9xdbf4VS5__7xezJel47RO5QqltKA1q6xrHQVrqW0ll4Agq7ZmWlN0upa8WXGkfCWcZUwpKfKUrXDVMTnb9m7C8G_EmMzaR4ddZ3scxmhqJYALBu-CVNQ18KrOIN-CLgwxBmzNJvi1Da-Ggpkkm8mgmQwaPX2yZKNz7HTXP67W2OxDO6t5_3W3t9HZrg22dz7usYpxKqjI2Pcthlnai8dgovPYO2x8QJdMM_i37_gPrVOV0Q</recordid><startdate>19960801</startdate><enddate>19960801</enddate><creator>Conradi, Sebastian</creator><creator>Ronnevi, Lars-Olof</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19960801</creationdate><title>Pitfalls in the evaluation of isometric strength (TQNE) data in ALS</title><author>Conradi, Sebastian ; Ronnevi, Lars-Olof</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-be66a09923acfc10aa1af6460e063f72991ec9764db4e14b5ca2288652286f5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Aged</topic><topic>Amyotrophic lateral sclerosis</topic><topic>Amyotrophic Lateral Sclerosis - physiopathology</topic><topic>Biological and medical sciences</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Disease Progression</topic><topic>Electromyography - standards</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Humans</topic><topic>Isometric Contraction - physiology</topic><topic>Isometric strength</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Muscular Atrophy, Spinal - physiopathology</topic><topic>Neurology</topic><topic>Neuromuscular disease</topic><topic>Regression Analysis</topic><topic>Respiration</topic><topic>Respiratory Function Tests</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Conradi, Sebastian</creatorcontrib><creatorcontrib>Ronnevi, Lars-Olof</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the neurological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Conradi, Sebastian</au><au>Ronnevi, Lars-Olof</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pitfalls in the evaluation of isometric strength (TQNE) data in ALS</atitle><jtitle>Journal of the neurological sciences</jtitle><addtitle>J Neurol Sci</addtitle><date>1996-08-01</date><risdate>1996</risdate><volume>139</volume><issue>suppl</issue><spage>60</spage><epage>63</epage><pages>60-63</pages><issn>0022-510X</issn><eissn>1878-5883</eissn><coden>JNSCAG</coden><abstract>The phase of rapid reduction of isometric strength in single muscle groups was identified and its slope was calculated in patients studied with the TQNE method. 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| ispartof | Journal of the neurological sciences, 1996-08, Vol.139 (suppl), p.60-63 |
| issn | 0022-510X 1878-5883 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - physiopathology Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Progression Electromyography - standards Evaluation Studies as Topic Female Humans Isometric Contraction - physiology Isometric strength Male Medical sciences Middle Aged Muscular Atrophy, Spinal - physiopathology Neurology Neuromuscular disease Regression Analysis Respiration Respiratory Function Tests |
| title | Pitfalls in the evaluation of isometric strength (TQNE) data in ALS |
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