I-131 Metaiodobenzylguanidine Uptake in a Parathyroid Adenoma
We describe a patient with multicentric small bowel carcinoids, severe hypertension, primary hyperparathyroidism, and multiple parathyroid adenomas. Intense uptake of I-131 metaiodobenzylguanidine (MIBG) occurred in a parathyroid adenoma. There was no biochemical evidence of catecholamine secretion...
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| Veröffentlicht in: | Clinical nuclear medicine 1988-09, Vol.13 (9), p.632-634 |
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| container_title | Clinical nuclear medicine |
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| creator | HAYWARD, ROBERT S BOWERING, C KEITH WARSHAWSKI, ROBERT S |
| description | We describe a patient with multicentric small bowel carcinoids, severe hypertension, primary hyperparathyroidism, and multiple parathyroid adenomas. Intense uptake of I-131 metaiodobenzylguanidine (MIBG) occurred in a parathyroid adenoma. There was no biochemical evidence of catecholamine secretion by the tumor but elevated serum levels of parathyroid hormone were demonstrated. We suspect that occasional parathyroid adenomas, like other APUDomas, may give false positive results when MIBG imaging is used to search for pheochromocytomas. This observation supports the inclusion of the parathyroid chief cells in the amine precursor uptake and decarboxylation (APUD) cell system. |
| doi_str_mv | 10.1097/00003072-198809000-00002 |
| format | Article |
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Intense uptake of I-131 metaiodobenzylguanidine (MIBG) occurred in a parathyroid adenoma. There was no biochemical evidence of catecholamine secretion by the tumor but elevated serum levels of parathyroid hormone were demonstrated. We suspect that occasional parathyroid adenomas, like other APUDomas, may give false positive results when MIBG imaging is used to search for pheochromocytomas. This observation supports the inclusion of the parathyroid chief cells in the amine precursor uptake and decarboxylation (APUD) cell system.</description><identifier>ISSN: 0363-9762</identifier><identifier>EISSN: 1536-0229</identifier><identifier>DOI: 10.1097/00003072-198809000-00002</identifier><identifier>PMID: 3180608</identifier><identifier>CODEN: CNMEDK</identifier><language>eng</language><publisher>Philadelphia, PA: Lippincott-Raven Publishers</publisher><subject>3-Iodobenzylguanidine ; Adenoma - diagnostic imaging ; Aged ; Biological and medical sciences ; Endocrinopathies ; Female ; Humans ; Iodine Radioisotopes - therapeutic use ; Iodobenzenes ; Malignant tumors ; Medical sciences ; Neoplasms, Multiple Primary - diagnostic imaging ; Parathyroid Neoplasms - diagnostic imaging ; Parathyroids. Parafollicular cells. Cholecalciferol. 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Intense uptake of I-131 metaiodobenzylguanidine (MIBG) occurred in a parathyroid adenoma. There was no biochemical evidence of catecholamine secretion by the tumor but elevated serum levels of parathyroid hormone were demonstrated. We suspect that occasional parathyroid adenomas, like other APUDomas, may give false positive results when MIBG imaging is used to search for pheochromocytomas. This observation supports the inclusion of the parathyroid chief cells in the amine precursor uptake and decarboxylation (APUD) cell system.</description><subject>3-Iodobenzylguanidine</subject><subject>Adenoma - diagnostic imaging</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Endocrinopathies</subject><subject>Female</subject><subject>Humans</subject><subject>Iodine Radioisotopes - therapeutic use</subject><subject>Iodobenzenes</subject><subject>Malignant tumors</subject><subject>Medical sciences</subject><subject>Neoplasms, Multiple Primary - diagnostic imaging</subject><subject>Parathyroid Neoplasms - diagnostic imaging</subject><subject>Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)</subject><subject>Radionuclide Imaging</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kT1PwzAQhi0EglL4CUgZEFvgbCe2MzAgxEelIhhgti7xhQbSpNiJqvLrSWnphpeT33vOlp5jLOJwySHTVzAcCVrEPDMGsuEWryOxx0Y8lSoGIbJ9NgKpZJxpJY7YcQgfAFxxlRyyQ8kNKDAjdj2JueTRE3VYta7Nqfle1e89NpWrGoreFh1-UlQ1EUYv6LGbrXxbuejGUdPO8YQdlFgHOt3WMXu7v3u9fYynzw-T25tpXEiTiLgkKaDkuQMOuYQkAVmgNjmiU3nJNZWZRoeam8KIARjyXJMqU6MSAAdyzC427y58-9VT6Oy8CgXVNTbU9sFqkwJP02wAzQYsfBuCp9IufDVHv7Ic7Nqc_TNnd-Z-IzGMnm3_6PM5ud3gVtXQP9_2MRRYlx6bogo7TItEZYP7MUs22LKtO_Lhs-6X5O2MsO5m9r-9yR-azYP8</recordid><startdate>198809</startdate><enddate>198809</enddate><creator>HAYWARD, ROBERT S</creator><creator>BOWERING, C KEITH</creator><creator>WARSHAWSKI, ROBERT S</creator><general>Lippincott-Raven Publishers</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198809</creationdate><title>I-131 Metaiodobenzylguanidine Uptake in a Parathyroid Adenoma</title><author>HAYWARD, ROBERT S ; BOWERING, C KEITH ; WARSHAWSKI, ROBERT S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3842-fe320f1bd010b304403ca78baad6bf17ef97ada718c82b30aadb7e6f586400d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>3-Iodobenzylguanidine</topic><topic>Adenoma - diagnostic imaging</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Endocrinopathies</topic><topic>Female</topic><topic>Humans</topic><topic>Iodine Radioisotopes - therapeutic use</topic><topic>Iodobenzenes</topic><topic>Malignant tumors</topic><topic>Medical sciences</topic><topic>Neoplasms, Multiple Primary - diagnostic imaging</topic><topic>Parathyroid Neoplasms - diagnostic imaging</topic><topic>Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)</topic><topic>Radionuclide Imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HAYWARD, ROBERT S</creatorcontrib><creatorcontrib>BOWERING, C KEITH</creatorcontrib><creatorcontrib>WARSHAWSKI, ROBERT S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HAYWARD, ROBERT S</au><au>BOWERING, C KEITH</au><au>WARSHAWSKI, ROBERT S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>I-131 Metaiodobenzylguanidine Uptake in a Parathyroid Adenoma</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>1988-09</date><risdate>1988</risdate><volume>13</volume><issue>9</issue><spage>632</spage><epage>634</epage><pages>632-634</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><coden>CNMEDK</coden><abstract>We describe a patient with multicentric small bowel carcinoids, severe hypertension, primary hyperparathyroidism, and multiple parathyroid adenomas. Intense uptake of I-131 metaiodobenzylguanidine (MIBG) occurred in a parathyroid adenoma. There was no biochemical evidence of catecholamine secretion by the tumor but elevated serum levels of parathyroid hormone were demonstrated. We suspect that occasional parathyroid adenomas, like other APUDomas, may give false positive results when MIBG imaging is used to search for pheochromocytomas. This observation supports the inclusion of the parathyroid chief cells in the amine precursor uptake and decarboxylation (APUD) cell system.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>3180608</pmid><doi>10.1097/00003072-198809000-00002</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0363-9762 |
| ispartof | Clinical nuclear medicine, 1988-09, Vol.13 (9), p.632-634 |
| issn | 0363-9762 1536-0229 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | 3-Iodobenzylguanidine Adenoma - diagnostic imaging Aged Biological and medical sciences Endocrinopathies Female Humans Iodine Radioisotopes - therapeutic use Iodobenzenes Malignant tumors Medical sciences Neoplasms, Multiple Primary - diagnostic imaging Parathyroid Neoplasms - diagnostic imaging Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases) Radionuclide Imaging |
| title | I-131 Metaiodobenzylguanidine Uptake in a Parathyroid Adenoma |
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