The antinociceptive effect and pharmacokinetics of olvanil following oral and subcutaneous dosing in the mouse

Mice were tested for response latency on a 55°C hot plate after subcutaneous (S.C.) or oral administration of olvanil (dose level 200 and 300 mg/kg, respectively). Only the S.C. injection of olvanil produced antinociception. A pharmacokinetics experiment with radiolabeled olvanil (200 mg/kg) was con...

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