Characterization of protein kinase C and its isoforms in human T lymphocytes

Protein kinase C (PKC) regulates numerous T cell functions and is present in abundance in normal human T cells and certain T cell lines. Although crude Triton X-100 soluble material obtained from T cell pellets contains minimal PKC activity, DEAE chromatography revealed that 12 to 37% of cellular PK...

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Veröffentlicht in:	The Journal of immunology (1950) 1988-11, Vol.141 (10), p.3463-3470
Hauptverfasser:	Beyers, AD, Hanekom, C, Rheeder, A, Strachan, AF, Wooten, MW, Nel, AE
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Cell Line Cytosol - enzymology Diglycerides Enzyme Activation - drug effects Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Humans Isoenzymes - isolation & purification Isoenzymes - metabolism Kinetics Octoxynol Polyethylene Glycols Protein Kinase C - isolation & purification Protein Kinase C - metabolism Solubility Substrate Specificity T-Lymphocytes - drug effects T-Lymphocytes - enzymology Transferases
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