Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene

To define mechanisms regulating expression of M creatine kinase, the human gene including 5′-flanking DNA was cloned, characterized, and partially sequenced. The gene contains 8 exons interrupted by 7 introns spanning 17.5 kilobase pairs of DNA. The intron-exon splice sites were identified and confo...

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