Comparative study of combined GIFT and IVF-ET with GIFT alone

Twenty-eight couples with unexplained infertility, or with suboptimal spermatozoa were divided into two groups. One group underwent gamete intra-Fallopian transfer (GIFT), and the other had combined GIFT and in-vitro fertilization-embryo transfer (IVF-ET) (GET). There was a marked difference in preg...

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Veröffentlicht in:Human reproduction (Oxford) 1988-10, Vol.3 (7), p.877-879
Hauptverfasser: Leong, M.K.H., Leung, C.K.M., Marriott, V.M., Wong, C.J.Y., Chan, Y.M., Chan, H.H.Y., Tucker, M.J.
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container_end_page 879
container_issue 7
container_start_page 877
container_title Human reproduction (Oxford)
container_volume 3
creator Leong, M.K.H.
Leung, C.K.M.
Marriott, V.M.
Wong, C.J.Y.
Chan, Y.M.
Chan, H.H.Y.
Tucker, M.J.
description Twenty-eight couples with unexplained infertility, or with suboptimal spermatozoa were divided into two groups. One group underwent gamete intra-Fallopian transfer (GIFT), and the other had combined GIFT and in-vitro fertilization-embryo transfer (IVF-ET) (GET). There was a marked difference in pregnancy rates between the two groups, with the pregnancy rate surprisingly being less in the combined GET group; 10% for GET, as compared with 39% for GIFT alone. The results suggest that GIFT and IVF-ET are incompatible. Differences in the pregnancy rates may be explained by limitations in implantation, whereby the embryo-endometrium interaction that allows for implantation and continued embryonic development has a ‘single event capacity’, and once this interaction is initiated, the ‘implantation window’ is closed to other embryos that may arrive later in the uterus.
doi_str_mv 10.1093/oxfordjournals.humrep.a136801
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source MEDLINE; Oxford University Press Journals Archive
subjects Adult
Embryo Transfer
Female
Fertilization in Vitro
Gamete Intrafallopian Transfer
GIFT
Humans
infertility
IVF-ET
Pregnancy
pregnancy rate
title Comparative study of combined GIFT and IVF-ET with GIFT alone
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