Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain

Palmar fibromatosis (Dupuytren contracture) causes fibrosis of specific palmar fascial bands. These bands are subjected to repetitive mechanical strain in situ. Primary cell cultures were derived from (a) palmar fibromatosis from eight patients, (b) uninvolved palmar fascia (Skoog's fibers) fro...

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Veröffentlicht in:	Journal of orthopaedic research 1996-09, Vol.14 (5), p.722-728
Hauptverfasser:	Alman, Benjamin A., Greel, Debra A., Ruby, Leonard K., Goldberg, Michael J., Wolfe, Hubert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody Specificity Blotting, Northern Bromodeoxyuridine Cell Division - drug effects Cells, Cultured - cytology Cells, Cultured - physiology Dupuytren Contracture - genetics Dupuytren Contracture - physiopathology Fascia - cytology Fascia - physiology Gene Expression - physiology Gene Expression Regulation - drug effects Humans Neutralization Tests Platelet-Derived Growth Factor - genetics Platelet-Derived Growth Factor - immunology Procollagen - genetics RNA, Messenger - analysis Space life sciences Stress, Mechanical
Online-Zugang:	Volltext
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