Substrate recognition and splice site determination in yeast tRNA splicing

S. cerevisae tRNA introns interrupt the gene at a constant position in the anticodon loop. Pre-tRNAs are matured by an endonuclease and a ligase. The endonuclease alone can accurately release the intron from the pre-tRNA. Here, we investigate the mechanism of splice site selection by the endonucleas...

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Veröffentlicht in:	Cell 1988-11, Vol.55 (4), p.719-730
Hauptverfasser:	Reyes, Vicente M., Abelson, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Fundamental and applied biological sciences. Psychology Introns Molecular and cellular biology Molecular genetics Mutation Nucleic Acid Conformation Ribonuclease T1 - metabolism RNA Splicing Saccharomyces cerevisiae - genetics Transcription. Transcription factor. Splicing. Rna processing
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