PC-2, linear homoglucan with α-linkages, peripherally enhances the hippocampal long-term potentiation

To investigate central effectiveness of PC-2, a glucan from lichen Parmelia caperata with alpha(1-3)(1-4) linkages in the ratio 3:2, with regard to the long-term potentiation (LTP) of evoked potential. The extent of LTP, induced by high-frequency stimulation of medial perforant pathway, was evaluate...

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Veröffentlicht in:	Pharmaceutical research 1996-09, Vol.13 (9), p.1322-1326
Hauptverfasser:	SMRIGA, M, SAITO, H, SHIBATA, S, NARUI, T, OKUYAMA, T, NISHIYAMA, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenalectomy Animals Biological and medical sciences Carbohydrate Sequence Dentate Gyrus - drug effects Dentate Gyrus - physiology Evoked Potentials Glucans - isolation & purification Glucans - pharmacology Lichens - chemistry Long-Term Potentiation - drug effects Male Medical sciences Molecular Sequence Data Neuropharmacology Pharmacology. Drug treatments Polysaccharides - administration & dosage Polysaccharides - isolation & purification Polysaccharides - pharmacology Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Rats, Wistar
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