Evaluation of a rapid theophylline test strip assay in the emergency department setting
Test strips recently have become available to measure theophylline levels. One such test strip (AccuLevel ®) had not been tested in an actual clinical situation with nontechnician personnel. We prospectively evaluated the test strip on consecutive emergency department patients, comparing it with the...
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Veröffentlicht in: | Annals of emergency medicine 1988-10, Vol.17 (10), p.1029-1033 |
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creator | Hurley, William T Saglio, Stephen D Henley, Charles E Gatrell, Cloyd B |
description | Test strips recently have become available to measure theophylline levels. One such test strip (AccuLevel
®) had not been tested in an actual clinical situation with nontechnician personnel. We prospectively evaluated the test strip on consecutive emergency department patients, comparing it with the agglutination inhibition method used by our hospital laboratory. Nurses and medics who ran the test were given only a brief demonstration and explanation of the manufacturer's instructions. The 61 test strip levels correlated highly with the laboratory results (r = 0.92, slope = 0.89, y-intercept = 0.99). The test strip results were available in less time (mean of 0.51 hours vs 1.89 hours for the laboratory,
P < .0001). The most accurate readings were obtained by those who ran the test most frequently. Caffeine intake did not influence the test. Cost was significantly lower than charges at local hospitals. |
doi_str_mv | 10.1016/S0196-0644(88)80440-2 |
format | Article |
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®) had not been tested in an actual clinical situation with nontechnician personnel. We prospectively evaluated the test strip on consecutive emergency department patients, comparing it with the agglutination inhibition method used by our hospital laboratory. Nurses and medics who ran the test were given only a brief demonstration and explanation of the manufacturer's instructions. The 61 test strip levels correlated highly with the laboratory results (r = 0.92, slope = 0.89, y-intercept = 0.99). The test strip results were available in less time (mean of 0.51 hours vs 1.89 hours for the laboratory,
P < .0001). The most accurate readings were obtained by those who ran the test most frequently. Caffeine intake did not influence the test. Cost was significantly lower than charges at local hospitals.</description><subject>Analysis</subject><subject>Biological and medical sciences</subject><subject>Caffeine - administration & dosage</subject><subject>Emergency Service, Hospital</subject><subject>Evaluation Studies as Topic</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Prospective Studies</subject><subject>Reagent Strips</subject><subject>testing</subject><subject>theophylline</subject><subject>Theophylline - blood</subject><issn>0196-0644</issn><issn>1097-6760</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LJDEQhoO46OjuTxByENFDr0k6nU6fRGRWhQEPuuwx1KQrGukvk4ww_34zzjBXT3V4n7eqeAg54-w3Z1xdPzPeqIIpKS-1vtJMSlaIAzLjrKkLVSt2SGZ75JicxPjOGGuk4EfkqOR13TRsRv7NP6FbQfLjQEdHgQaYfEvTG47T27rr_IA0YUw0puAnCjHCmvphA1DsMbziYNe0xQlC6nHIHKbkh9ef5IeDLuKv3Twlf__MX-4eisXT_ePd7aKwUstUcC0FoGx0ha1Y6pJpcKLUooGaOwaSl84p68Apxmul1RKsaluBJYBEh6o8JRfbvVMYP1b5UdP7aLHrYMBxFU2tpa5yNYPVFrRhjDGgM1PwPYS14cxshJovoWZjy2htvoQakXtnuwOrZY_tvrUzmPPzXQ7RQucCDNbHPVaLquKNztjNFsMs49NjMNH67A5bH9Am047-m0f-A9bPk1k</recordid><startdate>19881001</startdate><enddate>19881001</enddate><creator>Hurley, William T</creator><creator>Saglio, Stephen D</creator><creator>Henley, Charles E</creator><creator>Gatrell, Cloyd B</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19881001</creationdate><title>Evaluation of a rapid theophylline test strip assay in the emergency department setting</title><author>Hurley, William T ; Saglio, Stephen D ; Henley, Charles E ; Gatrell, Cloyd B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-1842ae4985ed2b8308af23829a71f0a413ff6cfaf6017686bac6dd2e3aa4efe63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Analysis</topic><topic>Biological and medical sciences</topic><topic>Caffeine - administration & dosage</topic><topic>Emergency Service, Hospital</topic><topic>Evaluation Studies as Topic</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Prospective Studies</topic><topic>Reagent Strips</topic><topic>testing</topic><topic>theophylline</topic><topic>Theophylline - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hurley, William T</creatorcontrib><creatorcontrib>Saglio, Stephen D</creatorcontrib><creatorcontrib>Henley, Charles E</creatorcontrib><creatorcontrib>Gatrell, Cloyd B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hurley, William T</au><au>Saglio, Stephen D</au><au>Henley, Charles E</au><au>Gatrell, Cloyd B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of a rapid theophylline test strip assay in the emergency department setting</atitle><jtitle>Annals of emergency medicine</jtitle><addtitle>Ann Emerg Med</addtitle><date>1988-10-01</date><risdate>1988</risdate><volume>17</volume><issue>10</issue><spage>1029</spage><epage>1033</epage><pages>1029-1033</pages><issn>0196-0644</issn><eissn>1097-6760</eissn><coden>AEMED3</coden><abstract>Test strips recently have become available to measure theophylline levels. One such test strip (AccuLevel
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Analysis Biological and medical sciences Caffeine - administration & dosage Emergency Service, Hospital Evaluation Studies as Topic General pharmacology Humans Medical sciences Pharmacology. Drug treatments Prospective Studies Reagent Strips testing theophylline Theophylline - blood |
title | Evaluation of a rapid theophylline test strip assay in the emergency department setting |
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