Evaluation of a rapid theophylline test strip assay in the emergency department setting

Test strips recently have become available to measure theophylline levels. One such test strip (AccuLevel ®) had not been tested in an actual clinical situation with nontechnician personnel. We prospectively evaluated the test strip on consecutive emergency department patients, comparing it with the...

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Veröffentlicht in:Annals of emergency medicine 1988-10, Vol.17 (10), p.1029-1033
Hauptverfasser: Hurley, William T, Saglio, Stephen D, Henley, Charles E, Gatrell, Cloyd B
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container_end_page 1033
container_issue 10
container_start_page 1029
container_title Annals of emergency medicine
container_volume 17
creator Hurley, William T
Saglio, Stephen D
Henley, Charles E
Gatrell, Cloyd B
description Test strips recently have become available to measure theophylline levels. One such test strip (AccuLevel ®) had not been tested in an actual clinical situation with nontechnician personnel. We prospectively evaluated the test strip on consecutive emergency department patients, comparing it with the agglutination inhibition method used by our hospital laboratory. Nurses and medics who ran the test were given only a brief demonstration and explanation of the manufacturer's instructions. The 61 test strip levels correlated highly with the laboratory results (r = 0.92, slope = 0.89, y-intercept = 0.99). The test strip results were available in less time (mean of 0.51 hours vs 1.89 hours for the laboratory, P < .0001). The most accurate readings were obtained by those who ran the test most frequently. Caffeine intake did not influence the test. Cost was significantly lower than charges at local hospitals.
doi_str_mv 10.1016/S0196-0644(88)80440-2
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Analysis
Biological and medical sciences
Caffeine - administration & dosage
Emergency Service, Hospital
Evaluation Studies as Topic
General pharmacology
Humans
Medical sciences
Pharmacology. Drug treatments
Prospective Studies
Reagent Strips
testing
theophylline
Theophylline - blood
title Evaluation of a rapid theophylline test strip assay in the emergency department setting
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