Characterization of a new high-temperature-induced 66-kDa heat-shock protein, antigenically related to heat-shock protein 72

M‐14 human melanoma cells, following severe hyperthermic exposures, synthesized a heat‐shock protein of 66 kDa (hsp 66), in addition to the major “classic” heat‐shock proteins. This hsp 66 was not expressed following mild hyperthermic exposures sufficient to trigger the synthesis of the other heat‐s...

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