Cardiorenal Consequences of Dual Angiotensin Converting Enzyme and Neutral Endopeptidase 24.11 Inhibition in Transgenic Rats with an Extra Renin Gene

The cardiovascular consequences of mixed angiotensin converting enzyme and neutral endopeptidase (ACE/NEP) inhibition with alatriopril/alatrioprilat were compared with the consequences of endopeptidase (NEP) inhibition alone with (S)-thiorphan/ecadotril by determining the acute effects of the compou...

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Veröffentlicht in:	Hypertension Research 1996, Vol.19(3), pp.151-159
Hauptverfasser:	Wegner, Max, Hirth-Dietrich, Claudia, Knorr, Andreas, Dressel, Jürgen, Ganten, Detlev, Stasch, Johannes-Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine - analogs & derivatives Alanine - pharmacology alatriopril Angiotensin-Converting Enzyme Inhibitors - administration & dosage Animals Animals, Genetically Modified ANP Blood Pressure - drug effects Dioxoles - pharmacology Dose-Response Relationship, Drug ecadotril Gene Expression hypertension Hypertension - genetics Hypertension - metabolism Hypertension - physiopathology Neprilysin - antagonists & inhibitors Rats Renin - genetics Renin - metabolism TGR(mRen2)27
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