Production of IL-1 alpha and IL-1 beta by human skin equivalents parasitized by Sarcoptes scabiei

Human skin equivalents (HSEs) were used as a model to investigate interleukin (IL)-1α and IL-1β secretions by keratinocytes stimulated by Sarcoptes scabiei (SS). SS mites burrowed into the stratum corneum when placed on the surface of cultured HSEs. Mites lived for 14 days. Mites and mite products i...

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Veröffentlicht in:	The Journal of parasitology 1996-10, Vol.82 (5), p.719-723
Hauptverfasser:	Arlian, L.G, Vyszenski-Moher, D.L, Rapp, C.M, Hull, B.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences cells Cells, Cultured Culture Media Cytokines disease models Epithelial cells Fibroblasts Fibroblasts - cytology Fibroblasts - immunology Fibroblasts - parasitology growth factors hepatocyte growth factor Hepatocyte Growth Factor - pharmacology Hepatocytes Human parasitic diseases due to arthropods Humans immune response Immunology in vitro Infectious diseases inflammation interleukin-1 Interleukin-1 - biosynthesis interleukin-6 Interleukin-6 - pharmacology Keratinocytes Keratinocytes - cytology Keratinocytes - immunology Keratinocytes - parasitology Medical sciences Mites Parasitic diseases Recombinant Proteins - pharmacology Sarcoptes scabiei Sarcoptes scabiei - immunology Sarcoptes scabiei - physiology Scabies Secretion Skin Skin - cytology Skin - immunology Skin - parasitology T lymphocytes Up-Regulation
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