The production of superoxide anion and nitric oxide by cultured murine leukocytes and the accumulation of TNF-α in the conditioned media is inhibited by taurine chloramine

Taurine chloramine (Tau-C1) inhibits production of nitric oxide (NO) by activated peritoneal macrophages and attenuates accumulation of tumor necrosis factor-alpha (TNF-α) in the culture media, similar to that previously reported for activated RAW 264.7 cells. In addition, the effect of Tau-C1 and t...

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Veröffentlicht in:	Immunopharmacology 1996-09, Vol.34 (2-3), p.89-95
Hauptverfasser:	Kim, Chaekyun, Park, Eunkyue, Quinn, Michael R., Schuller-Levis, Georgia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Culture Media, Conditioned Female Fundamental and applied biological sciences. Psychology Inflammation Macrophage Macrophages, Peritoneal - metabolism Mice Mice, Inbred BALB C Molecular and cellular biology Neutrophils - metabolism Nitric oxide Nitric Oxide - biosynthesis Nitrites - metabolism Superoxide anion Superoxides - metabolism Taurine - analogs & derivatives Taurine - pharmacology Taurine chloramine Tumor necrosis factor Tumor Necrosis Factor-alpha - biosynthesis
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