Plasmodium falciparum : gp195 tripeptide repeat-specific monoclonal antibody inhibits parasite growth in vitro

Seven monoclonal antibodies (mAbs) were produced to the precursor of the merozoite surface antigens (MSA-1 or gp195) using the Plasmodium falciparum Uganda-Palo Alto isolate. Three mAbs (CE2, DB8, and EB2) reacted with epitopes on the 83-kDa N-terminal processing fragment by immunoprecipitation of r...

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Veröffentlicht in:	Experimental parasitology 1996-10, Vol.84 (1), p.74-83
Hauptverfasser:	LOCHER, C. P, TAM, L. Q, CHANG, S. P, MCBRIDE, J. S, SIDDIQUI, W. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - immunology Antibodies, Protozoan - biosynthesis Antibodies, Protozoan - immunology Antigens, Protozoan - chemistry Antigens, Protozoan - immunology Biological and medical sciences Enzyme-Linked Immunosorbent Assay Epitopes - chemistry Epitopes - immunology Fluorescent Antibody Technique, Indirect Human protozoal diseases Hybridomas Immunoblotting Infectious diseases Malaria Medical sciences Mice Molecular Sequence Data Parasitic diseases Plasmodium falciparum Plasmodium falciparum - growth & development Plasmodium falciparum - immunology Protozoal diseases Tropical medicine
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