First Pass Tc-99m MIBI Ventriculography in the Assessment of Left Ventricular Diastolic Function: A Comparison With Doppler Echocardiography
Tc-99m MIBI is used for myocardial imaging and firstpass studies. However, little is known about its utility in the assessment of left ventricular diastolic function. The authors retrospectively compared first pass studies of Tc-99m MIBI at rest with Doppler flow velocity measurements to assess left...
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| Veröffentlicht in: | Clinical nuclear medicine 1996-09, Vol.21 (9), p.679-684 |
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| container_title | Clinical nuclear medicine |
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| creator | SHARIFI, MOHSEN KHEDKAR, NANDA PELLER, PATRICK MARTINEZ, CHARLES SORKIN, RICHARD LAKIER, JEFFREY |
| description | Tc-99m MIBI is used for myocardial imaging and firstpass studies. However, little is known about its utility in the assessment of left ventricular diastolic function. The authors retrospectively compared first pass studies of Tc-99m MIBI at rest with Doppler flow velocity measurements to assess left ventricular diastolic performance. Thirty-nine patients who had both studies performed within 48 hours of each other were evaluated. Three indices of diastolic function were measured by first pass Tc-99m MIBI ventriculography and Doppler echocardiography1) Time to peak early diastolic velocity; 2) normalized peak filling rate; and 3) half filling fraction. The results demonstrated a correlation of 0.82 (P < 0.001), 0.82 (P < 0.001), and 0.53 (P = 0.001) for the above indices, respectively. This study indicates that the indices of left ventricular diastolic function by first pass Tc-99m MIBI compare favorably with those derived from Doppler flow velocity measurements in which the diagnostic value has been previously established. Both methods accurately reflect diastolic flow and may facilitate clinical evaluation of diastolic function. |
| doi_str_mv | 10.1097/00003072-199609000-00002 |
| format | Article |
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However, little is known about its utility in the assessment of left ventricular diastolic function. The authors retrospectively compared first pass studies of Tc-99m MIBI at rest with Doppler flow velocity measurements to assess left ventricular diastolic performance. Thirty-nine patients who had both studies performed within 48 hours of each other were evaluated. Three indices of diastolic function were measured by first pass Tc-99m MIBI ventriculography and Doppler echocardiography1) Time to peak early diastolic velocity; 2) normalized peak filling rate; and 3) half filling fraction. The results demonstrated a correlation of 0.82 (P < 0.001), 0.82 (P < 0.001), and 0.53 (P = 0.001) for the above indices, respectively. This study indicates that the indices of left ventricular diastolic function by first pass Tc-99m MIBI compare favorably with those derived from Doppler flow velocity measurements in which the diagnostic value has been previously established. 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However, little is known about its utility in the assessment of left ventricular diastolic function. The authors retrospectively compared first pass studies of Tc-99m MIBI at rest with Doppler flow velocity measurements to assess left ventricular diastolic performance. Thirty-nine patients who had both studies performed within 48 hours of each other were evaluated. Three indices of diastolic function were measured by first pass Tc-99m MIBI ventriculography and Doppler echocardiography1) Time to peak early diastolic velocity; 2) normalized peak filling rate; and 3) half filling fraction. The results demonstrated a correlation of 0.82 (P < 0.001), 0.82 (P < 0.001), and 0.53 (P = 0.001) for the above indices, respectively. This study indicates that the indices of left ventricular diastolic function by first pass Tc-99m MIBI compare favorably with those derived from Doppler flow velocity measurements in which the diagnostic value has been previously established. Both methods accurately reflect diastolic flow and may facilitate clinical evaluation of diastolic function.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Blood Flow Velocity</subject><subject>Cardiovascular system</subject><subject>Diastole</subject><subject>Echocardiography, Doppler</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mitral Valve - diagnostic imaging</subject><subject>Mitral Valve - physiopathology</subject><subject>Radionuclide Ventriculography</subject><subject>Regression Analysis</subject><subject>Retrospective Studies</subject><subject>Stroke Volume</subject><subject>Technetium Tc 99m Sestamibi</subject><subject>Ultrasonic investigative techniques</subject><subject>Ventricular Function, Left</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1ks9u1DAQxi0EKtvCIyD5gLil-E_Wjrkt22670qL2UOAYue6EGJw4eBxVfQcemiwblhNzGc18v_FI_oYQytk5Z0a_Z1NIpkXBjVHMTFWxb4lnZMGXUhVMCPOcLJhUsjBaiZfkFPE7Y1xxVZ6Qk6rSplJqQX5tfMJMby0ivXOFMR39tP24pV-gz8m7McRvyQ7tE_U9zS3QFSIgdpNKY0N30OR_qE30wlvMMXhHN2Pvso_9B7qi69gNNnmMPf3qc0sv4jAESPTStdHZ9ODnJa_Ii8YGhNdzPiOfN5d36-tid3O1Xa92hZPCiEIL3qh7Dc6xRgCrSik1s0vGjCpZtWy0K4FLMBWUTFVKlo5xu1RWgTNGCCbPyLvDu0OKP0fAXHceHYRge4gj1roqNZdCTWB1AF2KiAmaeki-s-mp5qzeG1H_NaI-GvGnJabRN_OO8b6Dh-Pg_POT_nbWLTobmmR75_GIScGlNnusPGCPMWRI-COMj5DqFmzIbf2_M5C_AVj_n4Q</recordid><startdate>199609</startdate><enddate>199609</enddate><creator>SHARIFI, MOHSEN</creator><creator>KHEDKAR, NANDA</creator><creator>PELLER, PATRICK</creator><creator>MARTINEZ, CHARLES</creator><creator>SORKIN, RICHARD</creator><creator>LAKIER, JEFFREY</creator><general>Lippincott-Raven Publishers</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199609</creationdate><title>First Pass Tc-99m MIBI Ventriculography in the Assessment of Left Ventricular Diastolic Function: A Comparison With Doppler Echocardiography</title><author>SHARIFI, MOHSEN ; KHEDKAR, NANDA ; PELLER, PATRICK ; MARTINEZ, CHARLES ; SORKIN, RICHARD ; LAKIER, JEFFREY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3292-721f6b7ecc0f2e0843370a500964085f7c4e13e98e4068634c01a56a6ec992203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Blood Flow Velocity</topic><topic>Cardiovascular system</topic><topic>Diastole</topic><topic>Echocardiography, Doppler</topic><topic>Female</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mitral Valve - diagnostic imaging</topic><topic>Mitral Valve - physiopathology</topic><topic>Radionuclide Ventriculography</topic><topic>Regression Analysis</topic><topic>Retrospective Studies</topic><topic>Stroke Volume</topic><topic>Technetium Tc 99m Sestamibi</topic><topic>Ultrasonic investigative techniques</topic><topic>Ventricular Function, Left</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SHARIFI, MOHSEN</creatorcontrib><creatorcontrib>KHEDKAR, NANDA</creatorcontrib><creatorcontrib>PELLER, PATRICK</creatorcontrib><creatorcontrib>MARTINEZ, CHARLES</creatorcontrib><creatorcontrib>SORKIN, RICHARD</creatorcontrib><creatorcontrib>LAKIER, JEFFREY</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SHARIFI, MOHSEN</au><au>KHEDKAR, NANDA</au><au>PELLER, PATRICK</au><au>MARTINEZ, CHARLES</au><au>SORKIN, RICHARD</au><au>LAKIER, JEFFREY</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>First Pass Tc-99m MIBI Ventriculography in the Assessment of Left Ventricular Diastolic Function: A Comparison With Doppler Echocardiography</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>1996-09</date><risdate>1996</risdate><volume>21</volume><issue>9</issue><spage>679</spage><epage>684</epage><pages>679-684</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><coden>CNMEDK</coden><abstract>Tc-99m MIBI is used for myocardial imaging and firstpass studies. However, little is known about its utility in the assessment of left ventricular diastolic function. The authors retrospectively compared first pass studies of Tc-99m MIBI at rest with Doppler flow velocity measurements to assess left ventricular diastolic performance. Thirty-nine patients who had both studies performed within 48 hours of each other were evaluated. Three indices of diastolic function were measured by first pass Tc-99m MIBI ventriculography and Doppler echocardiography1) Time to peak early diastolic velocity; 2) normalized peak filling rate; and 3) half filling fraction. The results demonstrated a correlation of 0.82 (P < 0.001), 0.82 (P < 0.001), and 0.53 (P = 0.001) for the above indices, respectively. This study indicates that the indices of left ventricular diastolic function by first pass Tc-99m MIBI compare favorably with those derived from Doppler flow velocity measurements in which the diagnostic value has been previously established. Both methods accurately reflect diastolic flow and may facilitate clinical evaluation of diastolic function.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>8879866</pmid><doi>10.1097/00003072-199609000-00002</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0363-9762 |
| ispartof | Clinical nuclear medicine, 1996-09, Vol.21 (9), p.679-684 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Blood Flow Velocity Cardiovascular system Diastole Echocardiography, Doppler Female Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Mitral Valve - diagnostic imaging Mitral Valve - physiopathology Radionuclide Ventriculography Regression Analysis Retrospective Studies Stroke Volume Technetium Tc 99m Sestamibi Ultrasonic investigative techniques Ventricular Function, Left |
| title | First Pass Tc-99m MIBI Ventriculography in the Assessment of Left Ventricular Diastolic Function: A Comparison With Doppler Echocardiography |
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