A monoclonal antibody that recognizes a 110-kDa protein primarily located on the platelet α-granule, which is translocated to and upgraded on the surface membrane of platelets upon activation

A murine monoclonal antibody, designated as MAb AAP2, was produced by immunizing human activated platelets to BALB/c mice. MAb AAP2 recognizes a platelet membrane antigen that was present in trace amount on the membrane of resting platelets, and was strongly expressed on the membrane after activatio...

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Veröffentlicht in:	Hybridoma 1996-08, Vol.15 (4), p.271-278
Hauptverfasser:	LIAN, E. C.-Y, WU, X.-W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, immunoglobulins Antibodies, Monoclonal Antibody Specificity Biological and medical sciences Biological Transport Blood Platelets - immunology Cell Compartmentation Cell Membrane - immunology Centrifugation, Density Gradient Cytoplasmic Granules - immunology Fluorescent Antibody Technique, Indirect Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Membrane Proteins - immunology Membrane Proteins - metabolism Mice Mice, Inbred BALB C Microscopy, Immunoelectron Molecular immunology Molecular Weight Monoclonal antibodies Platelet Activation
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