A microcomputer based automated quantitative coronary angiographic analysis system
Rapid and accurate assessment of coronary artery stenotic severity is important in therapy and understanding of coronary artery disease. Since automated systems minimize prejudice and variations in analysis, we developed an automated, quantitative coronary analysis system utilizing an IBM PC-XT comp...
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| Veröffentlicht in: | Annals of biomedical engineering 1988-01, Vol.16 (4), p.367-377 |
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| container_end_page | 377 |
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| container_start_page | 367 |
| container_title | Annals of biomedical engineering |
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| creator | SANTAMORE, N. P KAHL, F. R KUTCHER, M. A NEGIN, M WHITEMAN, J. L KASE, J. P LITTLE, W. C |
| description | Rapid and accurate assessment of coronary artery stenotic severity is important in therapy and understanding of coronary artery disease. Since automated systems minimize prejudice and variations in analysis, we developed an automated, quantitative coronary analysis system utilizing an IBM PC-XT computer. Film images (35 mm) were cine-to-video converted and subsequently digitized by an IBM PC-XT computer. Given an approximate center line, the computer automatically detected edges, corrected for X-ray magnification, and calculated arterial dimensions. On objects of known dimensional sizes, the correlation coefficient between actual and calculated dimensions was 0.996 (p less than 0.01) with a standard error of estimate of 0.07 mm and +/- 3.0% reproducibility. For objects less than 1 mm in diameter, the standard error of estimate was 0.05 mm with +/- 4.1% reproducibility. However, with minimal contrast material (25%), the standard error of estimate increased to 0.20 mm with +/- 7.2% reproducibility. The results indicate that automated, quantitative coronary angiography can be achieved using an inexpensive IBM PC-XT based system, provided that the vessels are adequately opacified. |
| doi_str_mv | 10.1007/bf02364624 |
| format | Article |
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P ; KAHL, F. R ; KUTCHER, M. A ; NEGIN, M ; WHITEMAN, J. L ; KASE, J. P ; LITTLE, W. C</creator><creatorcontrib>SANTAMORE, N. P ; KAHL, F. R ; KUTCHER, M. A ; NEGIN, M ; WHITEMAN, J. L ; KASE, J. P ; LITTLE, W. C</creatorcontrib><description>Rapid and accurate assessment of coronary artery stenotic severity is important in therapy and understanding of coronary artery disease. Since automated systems minimize prejudice and variations in analysis, we developed an automated, quantitative coronary analysis system utilizing an IBM PC-XT computer. Film images (35 mm) were cine-to-video converted and subsequently digitized by an IBM PC-XT computer. Given an approximate center line, the computer automatically detected edges, corrected for X-ray magnification, and calculated arterial dimensions. On objects of known dimensional sizes, the correlation coefficient between actual and calculated dimensions was 0.996 (p less than 0.01) with a standard error of estimate of 0.07 mm and +/- 3.0% reproducibility. For objects less than 1 mm in diameter, the standard error of estimate was 0.05 mm with +/- 4.1% reproducibility. However, with minimal contrast material (25%), the standard error of estimate increased to 0.20 mm with +/- 7.2% reproducibility. The results indicate that automated, quantitative coronary angiography can be achieved using an inexpensive IBM PC-XT based system, provided that the vessels are adequately opacified.</description><identifier>ISSN: 0090-6964</identifier><identifier>EISSN: 1573-9686</identifier><identifier>DOI: 10.1007/bf02364624</identifier><identifier>PMID: 3177983</identifier><identifier>CODEN: ABMECF</identifier><language>eng</language><publisher>New York, NY: Springer</publisher><subject>Adult ; Biological and medical sciences ; Cardiovascular system ; Coronary Angiography ; Coronary Disease - diagnostic imaging ; Humans ; Image Processing, Computer-Assisted - methods ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Microcomputers ; Radiodiagnosis. Nmr imagery. 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Given an approximate center line, the computer automatically detected edges, corrected for X-ray magnification, and calculated arterial dimensions. On objects of known dimensional sizes, the correlation coefficient between actual and calculated dimensions was 0.996 (p less than 0.01) with a standard error of estimate of 0.07 mm and +/- 3.0% reproducibility. For objects less than 1 mm in diameter, the standard error of estimate was 0.05 mm with +/- 4.1% reproducibility. However, with minimal contrast material (25%), the standard error of estimate increased to 0.20 mm with +/- 7.2% reproducibility. The results indicate that automated, quantitative coronary angiography can be achieved using an inexpensive IBM PC-XT based system, provided that the vessels are adequately opacified.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>Coronary Angiography</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microcomputers</subject><subject>Radiodiagnosis. Nmr imagery. 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| ispartof | Annals of biomedical engineering, 1988-01, Vol.16 (4), p.367-377 |
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| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Biological and medical sciences Cardiovascular system Coronary Angiography Coronary Disease - diagnostic imaging Humans Image Processing, Computer-Assisted - methods Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Microcomputers Radiodiagnosis. Nmr imagery. Nmr spectrometry |
| title | A microcomputer based automated quantitative coronary angiographic analysis system |
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