Scopolamine-induced suppression of paradoxical sleep is reversed by the somatostatin analogue SMS 201–995 in rats

The intraperitoneal administration of the octapeptide somatostatin analogue SMS 201–995 produced a significant increase in paradoxical sleep (PS) in rats. The suppression of PS by the muscarinic receptor blocker scopolamine was reversed by SMS 201–995. These findings confirm previous results demonst...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1988-06, Vol.30 (2), p.295-297
Hauptverfasser:	Danguir, Jaber, De Saint-Hilaire-Kafi, Sarah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Fundamental and applied biological sciences. Psychology Male Octreotide - pharmacology Paradoxical sleep Rats Rats, Inbred Strains Scopolamine Scopolamine - antagonists & inhibitors Sleep, REM - drug effects Sleep. Vigilance Somatostatin Somatostatin analogue Vertebrates: nervous system and sense organs
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