Simultaneous aortic reconstruction and bilateral renal revascularization: Is this a safe and effective procedure?
Between 1982 and 1987, 32 patients with severe aortorenal atherosclerosis had simultaneous aortic and bilateral renal revascularization. All patients were hypertensive. Eighteen patients (56%) had renal insufficiency with a mean serum creatinine (SC) of 2.8 mg/dl. Nine patients had an aortic aneurys...
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Veröffentlicht in: | Journal of vascular surgery 1988-10, Vol.8 (4), p.357-366 |
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description | Between 1982 and 1987, 32 patients with severe aortorenal atherosclerosis had simultaneous aortic and bilateral renal revascularization. All patients were hypertensive. Eighteen patients (56%) had renal insufficiency with a mean serum creatinine (SC) of 2.8 mg/dl. Nine patients had an aortic aneurysm; the remaining 23 patients had aortoiliac occlusive disease of varying severity. Aortic reconstruction was done with either a straight (six patients) or bifurcated (26 patients) Dacron graft. Renal revascularization was accomplished with either bypass (60 arteries) or transaortic endarterectomy (four arteries). One patient died of pulmonary embolism (operative mortality rate 3%). Beneficial blood pressure response was achieved in 28 of 31 survivors, (90%). Among the 18 patients with renal insufficiency, mean SC was 2.80 ± 1.18 mg/dl preoperatively and 1.65 ± 0.48 mg/dl postoperatively (p < 0.001). Among eight patients with severe renal dysfunction before surgery (SC greater than 3 mg/dl), mean SC was 3.90 ± 0.85 mg/dl before and 1.79 ± 0.69 mg/dl after operation (p < 0.001). In follow-up extending to 58 months (mean 27.6 months), five late deaths occurred; cumulative survival was 94% at 2 years and 60% at 4 years. There were no instances of worsening hypertension; one patient had deteriorating renal function. These results indicate that severe aortorenal atherosclerosis can be managed with simultaneous aortic reconstruction and bilateral renal revascularization at low operative risk. In addition, there can be high expectation of significant and persisting benefit in both hypertension and renal dysfunction after operation. |
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All patients were hypertensive. Eighteen patients (56%) had renal insufficiency with a mean serum creatinine (SC) of 2.8 mg/dl. Nine patients had an aortic aneurysm; the remaining 23 patients had aortoiliac occlusive disease of varying severity. Aortic reconstruction was done with either a straight (six patients) or bifurcated (26 patients) Dacron graft. Renal revascularization was accomplished with either bypass (60 arteries) or transaortic endarterectomy (four arteries). One patient died of pulmonary embolism (operative mortality rate 3%). Beneficial blood pressure response was achieved in 28 of 31 survivors, (90%). Among the 18 patients with renal insufficiency, mean SC was 2.80 ± 1.18 mg/dl preoperatively and 1.65 ± 0.48 mg/dl postoperatively (p < 0.001). Among eight patients with severe renal dysfunction before surgery (SC greater than 3 mg/dl), mean SC was 3.90 ± 0.85 mg/dl before and 1.79 ± 0.69 mg/dl after operation (p < 0.001). In follow-up extending to 58 months (mean 27.6 months), five late deaths occurred; cumulative survival was 94% at 2 years and 60% at 4 years. There were no instances of worsening hypertension; one patient had deteriorating renal function. These results indicate that severe aortorenal atherosclerosis can be managed with simultaneous aortic reconstruction and bilateral renal revascularization at low operative risk. In addition, there can be high expectation of significant and persisting benefit in both hypertension and renal dysfunction after operation.</description><identifier>ISSN: 0741-5214</identifier><identifier>EISSN: 1097-6809</identifier><identifier>DOI: 10.1016/0741-5214(88)90096-1</identifier><identifier>PMID: 2971824</identifier><identifier>CODEN: JVSUES</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Aged ; Aorta, Abdominal - surgery ; Aortic Diseases - mortality ; Aortic Diseases - surgery ; Arteriosclerosis - mortality ; Arteriosclerosis - surgery ; Biological and medical sciences ; Blood Vessel Prosthesis ; Endarterectomy ; Female ; Follow-Up Studies ; Humans ; Male ; Medical sciences ; Middle Aged ; Polyethylene Terephthalates ; Renal Artery - surgery ; Renal Artery Obstruction - mortality ; Renal Artery Obstruction - surgery ; Risk Factors ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</subject><ispartof>Journal of vascular surgery, 1988-10, Vol.8 (4), p.357-366</ispartof><rights>1988</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0741521488900961$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3537,23909,23910,25118,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7265361$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2971824$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>O'Mara, Charles S.</creatorcontrib><creatorcontrib>Maples, Michael D.</creatorcontrib><creatorcontrib>Kilgore, Thomas L.</creatorcontrib><creatorcontrib>McMullan, Martin H.</creatorcontrib><creatorcontrib>Tyler, Henry B.</creatorcontrib><creatorcontrib>Mundinger, Gerhard H.</creatorcontrib><creatorcontrib>Kennedy, Ronald E.</creatorcontrib><title>Simultaneous aortic reconstruction and bilateral renal revascularization: Is this a safe and effective procedure?</title><title>Journal of vascular surgery</title><addtitle>J Vasc Surg</addtitle><description>Between 1982 and 1987, 32 patients with severe aortorenal atherosclerosis had simultaneous aortic and bilateral renal revascularization. All patients were hypertensive. Eighteen patients (56%) had renal insufficiency with a mean serum creatinine (SC) of 2.8 mg/dl. Nine patients had an aortic aneurysm; the remaining 23 patients had aortoiliac occlusive disease of varying severity. Aortic reconstruction was done with either a straight (six patients) or bifurcated (26 patients) Dacron graft. Renal revascularization was accomplished with either bypass (60 arteries) or transaortic endarterectomy (four arteries). One patient died of pulmonary embolism (operative mortality rate 3%). Beneficial blood pressure response was achieved in 28 of 31 survivors, (90%). Among the 18 patients with renal insufficiency, mean SC was 2.80 ± 1.18 mg/dl preoperatively and 1.65 ± 0.48 mg/dl postoperatively (p < 0.001). Among eight patients with severe renal dysfunction before surgery (SC greater than 3 mg/dl), mean SC was 3.90 ± 0.85 mg/dl before and 1.79 ± 0.69 mg/dl after operation (p < 0.001). In follow-up extending to 58 months (mean 27.6 months), five late deaths occurred; cumulative survival was 94% at 2 years and 60% at 4 years. There were no instances of worsening hypertension; one patient had deteriorating renal function. These results indicate that severe aortorenal atherosclerosis can be managed with simultaneous aortic reconstruction and bilateral renal revascularization at low operative risk. In addition, there can be high expectation of significant and persisting benefit in both hypertension and renal dysfunction after operation.</description><subject>Aged</subject><subject>Aorta, Abdominal - surgery</subject><subject>Aortic Diseases - mortality</subject><subject>Aortic Diseases - surgery</subject><subject>Arteriosclerosis - mortality</subject><subject>Arteriosclerosis - surgery</subject><subject>Biological and medical sciences</subject><subject>Blood Vessel Prosthesis</subject><subject>Endarterectomy</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Polyethylene Terephthalates</subject><subject>Renal Artery - surgery</subject><subject>Renal Artery Obstruction - mortality</subject><subject>Renal Artery Obstruction - surgery</subject><subject>Risk Factors</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</subject><issn>0741-5214</issn><issn>1097-6809</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kU9r3DAQxUVI2GzSfoMUfAghPbjVyJIt9dAQQpouLOTQ9ixkeUQVvPauJC-kn77aP-xFc3i_eeLNI-QG6BegUH-lDYdSMOD3Un5WlKq6hDMyB6qaspZUnZP5CbkkVzG-UQogZDMjM6YakIzPyeaXX019MgOOUyzMGJK3RUA7DjGFySY_DoUZuqL1vUkYTJ_FYf9uTbRTb4L_Z3bUt2IRi_TXZ5MiGof7LXQOs8cWi3UYLXZTwIcP5MKZPuLH47wmf348_376WS5fXxZPj8sSGRWp7BgH1XLhGIrKcWcsdLTrmOCUOlQcJUdlbSVMbdtWtiaHowzyFK5VFauuyd3BN3-9mTAmvfLRYt8fsupG8lpJaDL46QhO7Qo7vQ5-ZcK7Pt4o67dHPSc2vQtmsD6esIbVoqohY98PGOZQW49BR-txyKl9vmfS3eg1UL2rTu960btetJR6X52G6j9Do4xX</recordid><startdate>198810</startdate><enddate>198810</enddate><creator>O'Mara, Charles S.</creator><creator>Maples, Michael D.</creator><creator>Kilgore, Thomas L.</creator><creator>McMullan, Martin H.</creator><creator>Tyler, Henry B.</creator><creator>Mundinger, Gerhard H.</creator><creator>Kennedy, Ronald E.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198810</creationdate><title>Simultaneous aortic reconstruction and bilateral renal revascularization: Is this a safe and effective procedure?</title><author>O'Mara, Charles S. ; Maples, Michael D. ; Kilgore, Thomas L. ; McMullan, Martin H. ; Tyler, Henry B. ; Mundinger, Gerhard H. ; Kennedy, Ronald E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e205t-d2419b45f2e53f4fac1d0dd25400fe94e84e9cc35a6cbb8ba001021ba05fb9323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Aged</topic><topic>Aorta, Abdominal - surgery</topic><topic>Aortic Diseases - mortality</topic><topic>Aortic Diseases - surgery</topic><topic>Arteriosclerosis - mortality</topic><topic>Arteriosclerosis - surgery</topic><topic>Biological and medical sciences</topic><topic>Blood Vessel Prosthesis</topic><topic>Endarterectomy</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Polyethylene Terephthalates</topic><topic>Renal Artery - surgery</topic><topic>Renal Artery Obstruction - mortality</topic><topic>Renal Artery Obstruction - surgery</topic><topic>Risk Factors</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>O'Mara, Charles S.</creatorcontrib><creatorcontrib>Maples, Michael D.</creatorcontrib><creatorcontrib>Kilgore, Thomas L.</creatorcontrib><creatorcontrib>McMullan, Martin H.</creatorcontrib><creatorcontrib>Tyler, Henry B.</creatorcontrib><creatorcontrib>Mundinger, Gerhard H.</creatorcontrib><creatorcontrib>Kennedy, Ronald E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of vascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O'Mara, Charles S.</au><au>Maples, Michael D.</au><au>Kilgore, Thomas L.</au><au>McMullan, Martin H.</au><au>Tyler, Henry B.</au><au>Mundinger, Gerhard H.</au><au>Kennedy, Ronald E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Simultaneous aortic reconstruction and bilateral renal revascularization: Is this a safe and effective procedure?</atitle><jtitle>Journal of vascular surgery</jtitle><addtitle>J Vasc Surg</addtitle><date>1988-10</date><risdate>1988</risdate><volume>8</volume><issue>4</issue><spage>357</spage><epage>366</epage><pages>357-366</pages><issn>0741-5214</issn><eissn>1097-6809</eissn><coden>JVSUES</coden><abstract>Between 1982 and 1987, 32 patients with severe aortorenal atherosclerosis had simultaneous aortic and bilateral renal revascularization. All patients were hypertensive. Eighteen patients (56%) had renal insufficiency with a mean serum creatinine (SC) of 2.8 mg/dl. Nine patients had an aortic aneurysm; the remaining 23 patients had aortoiliac occlusive disease of varying severity. Aortic reconstruction was done with either a straight (six patients) or bifurcated (26 patients) Dacron graft. Renal revascularization was accomplished with either bypass (60 arteries) or transaortic endarterectomy (four arteries). One patient died of pulmonary embolism (operative mortality rate 3%). Beneficial blood pressure response was achieved in 28 of 31 survivors, (90%). Among the 18 patients with renal insufficiency, mean SC was 2.80 ± 1.18 mg/dl preoperatively and 1.65 ± 0.48 mg/dl postoperatively (p < 0.001). Among eight patients with severe renal dysfunction before surgery (SC greater than 3 mg/dl), mean SC was 3.90 ± 0.85 mg/dl before and 1.79 ± 0.69 mg/dl after operation (p < 0.001). In follow-up extending to 58 months (mean 27.6 months), five late deaths occurred; cumulative survival was 94% at 2 years and 60% at 4 years. There were no instances of worsening hypertension; one patient had deteriorating renal function. These results indicate that severe aortorenal atherosclerosis can be managed with simultaneous aortic reconstruction and bilateral renal revascularization at low operative risk. In addition, there can be high expectation of significant and persisting benefit in both hypertension and renal dysfunction after operation.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>2971824</pmid><doi>10.1016/0741-5214(88)90096-1</doi><tpages>10</tpages></addata></record> |
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subjects | Aged Aorta, Abdominal - surgery Aortic Diseases - mortality Aortic Diseases - surgery Arteriosclerosis - mortality Arteriosclerosis - surgery Biological and medical sciences Blood Vessel Prosthesis Endarterectomy Female Follow-Up Studies Humans Male Medical sciences Middle Aged Polyethylene Terephthalates Renal Artery - surgery Renal Artery Obstruction - mortality Renal Artery Obstruction - surgery Risk Factors Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels |
title | Simultaneous aortic reconstruction and bilateral renal revascularization: Is this a safe and effective procedure? |
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