Reactivity of eleven anti-human leucocyte monoclonal antibodies with lymphocytes from several domestic animals

Nine commercially available monoclonal antibodies and two monoclonal antibodies from The American Type Culture Collection, raised against various human leucocyte surface antigens, were tested on lymphocytes from cow, sheep, goat, swine, horse, cat, dog, mink, and rabbit as well as man. Four antibodi...

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Veröffentlicht in:Veterinary immunology and immunopathology 1988, Vol.19 (1), p.31-38
Hauptverfasser: Aasted, Bent, Blixenkrone-Møller, Merete, Larsen, Else Bang, Ohmann, Helle Bielefeldt, Simesen, Ruth Buemann, Uttenthal, Åse
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container_end_page 38
container_issue 1
container_start_page 31
container_title Veterinary immunology and immunopathology
container_volume 19
creator Aasted, Bent
Blixenkrone-Møller, Merete
Larsen, Else Bang
Ohmann, Helle Bielefeldt
Simesen, Ruth Buemann
Uttenthal, Åse
description Nine commercially available monoclonal antibodies and two monoclonal antibodies from The American Type Culture Collection, raised against various human leucocyte surface antigens, were tested on lymphocytes from cow, sheep, goat, swine, horse, cat, dog, mink, and rabbit as well as man. Four antibodies bound to lymphocytes from some of the animals. These were the antibodies against CD8 and CD4 antigen, the antibody to C3b-receptor, and the antibody to the HLA-DR antigen. The CD8 antigen-reactive antibody reacted with lymphocytes from mink, cat, dog, and sheep, while the CD4 antigen-reactive antibody reacted with lymphocytes from mink. The anti-C3b-R antibody reacted with lymphocytes from horse, swine, dog, and cat, and the anti-HLA-DR reacted with lymphocytes from cow, goat, sheep, horse, dog, cat, and mink.
doi_str_mv 10.1016/0165-2427(88)90044-X
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ispartof Veterinary immunology and immunopathology, 1988, Vol.19 (1), p.31-38
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Animals
Animals, Domestic - immunology
Antibodies, Monoclonal
ANTICORPS MONOCLONAL
ANTICUERPOS MONOCLONALES
Antigens, Differentiation, T-Lymphocyte - immunology
BETAIL
CD8 Antigens
Cross Reactions
GANADO
HLA-DR Antigens - immunology
Humans
IMMUNOLOGIE
IMMUNOLOGY
INMUNOLOGIA
Leukocytes - immunology
LINFOCITOS
LIVESTOCK
LYMPHOCYTE
LYMPHOCYTES
Lymphocytes - immunology
MONOCLONAL ANTIBODIES
Receptors, Complement - immunology
Receptors, Complement 3b
Species Specificity
title Reactivity of eleven anti-human leucocyte monoclonal antibodies with lymphocytes from several domestic animals
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