An estimation of pharmacokinetic parameters for each dosing at unequal doses and dosing intervals

The calculations of pharmacokinetic parameters for each dosing at unequal doses and dosing intervals were proposed. Systemic clearance of a drug following one-compartment open model can be determined by the product of the apparent first-order elimination rate constant and the apparent volume of dist...

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Veröffentlicht in:	Therapeutic drug monitoring 1988-01, Vol.10 (3), p.296-298
Hauptverfasser:	JOHNO, I, NAKAMURA, T, KITAZAWA, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biological Availability Drug Administration Schedule General pharmacology Humans Medical sciences Models, Biological Pharmacokinetics Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments
Online-Zugang:	Volltext
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