Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseases
Oral examinations were performed on 5 patients with hypophosphatemic bone disease (HBD) (2 males and 3 females), 14 patients with X-linked hypophosphatemia (XLH), and 4 affected XLH relatives (6 males and 12 females). The control subjects were the unaffected siblings and parents of the patients and...
Gespeichert in:
| Veröffentlicht in: | Oral surgery, oral medicine, oral pathology oral medicine, oral pathology, 1988-09, Vol.66 (3), p.310-314 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 314 |
|---|---|
| container_issue | 3 |
| container_start_page | 310 |
| container_title | Oral surgery, oral medicine, oral pathology |
| container_volume | 66 |
| creator | Schwartz, S. Scriver, C.R. Reade, T.M. Shields, E.D. |
| description | Oral examinations were performed on 5 patients with hypophosphatemic bone disease (HBD) (2 males and 3 females), 14 patients with X-linked hypophosphatemia (XLH), and 4 affected XLH relatives (6 males and 12 females). The control subjects were the unaffected siblings and parents of the patients and unrelated healthy, gender- and age-matched subjects. Serum phosphorus values were the same by disease type and gender in patients with HBD and XLH. They shared certain dental abnormalities, in particular pulpal necrosis and large pulp spaces. However, only patients with XLH had Class III malocclusions and mild enamel defects, and males with XLH had more severe occlusal and enamel defects than females with XLH. Different dental phenotypes are further evidence that XLH and HBD are different diseases. The dental abnormalities were not prevented by treatment, instituted early in life, which raised serum phosphorus to the near normal range. |
| doi_str_mv | 10.1016/0030-4220(88)90237-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78465388</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>003042208890237X</els_id><sourcerecordid>78465388</sourcerecordid><originalsourceid>FETCH-LOGICAL-c387t-6bbd85966f343ca6793dacf4dfbca35a68f3f3cada840200e6f63e6b50a341913</originalsourceid><addsrcrecordid>eNp9kUGL1TAUhYMo43P0Hyhko-iimjZtmroQZHBUGJiNwtuF2-TGRtu0JunI-zf-VFPfcwQXbhLC-e654RxCHpfsZclK8Yoxzoq6qthzKV90rOJtsb9DdqVsZVGVbXOX7G6R--RBjF_zs60FPyNnlawbXjU78vM6wEit88b5L5E6TxdIDn2K9IdLA4U1zXGeMmPmyXnwiQ6HZV6GOS4DJJycpv3skRoXESJS8Ibui9H5b2j-ReE1vVxDGjBQvHEGvUaaspQPPFAIm4u1GPL6P37xIblnYYz46HSfk8-X7z5dfCiurt9_vHh7VWgu21SIvjey6YSwvOYaRNtxA9rWxvYaeANCWm6zYEDWrGIMhRUcRd8w4HXZlfycPDv6LmH-vmJManJR4ziCx3mNqpW1aLiUGayPoA5zjAGtWoKbIBxUydRWjNpSV1vqSkr1uxi1z2NPTv5rP6G5HTo1kfWnJx2ihtEG8NrFv95d07CSt5l7c-Qwh3HjMKio3ZakcQF1UmZ2___ILzBDrp0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78465388</pqid></control><display><type>article</type><title>Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseases</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Schwartz, S. ; Scriver, C.R. ; Reade, T.M. ; Shields, E.D.</creator><creatorcontrib>Schwartz, S. ; Scriver, C.R. ; Reade, T.M. ; Shields, E.D.</creatorcontrib><description>Oral examinations were performed on 5 patients with hypophosphatemic bone disease (HBD) (2 males and 3 females), 14 patients with X-linked hypophosphatemia (XLH), and 4 affected XLH relatives (6 males and 12 females). The control subjects were the unaffected siblings and parents of the patients and unrelated healthy, gender- and age-matched subjects. Serum phosphorus values were the same by disease type and gender in patients with HBD and XLH. They shared certain dental abnormalities, in particular pulpal necrosis and large pulp spaces. However, only patients with XLH had Class III malocclusions and mild enamel defects, and males with XLH had more severe occlusal and enamel defects than females with XLH. Different dental phenotypes are further evidence that XLH and HBD are different diseases. The dental abnormalities were not prevented by treatment, instituted early in life, which raised serum phosphorus to the near normal range.</description><identifier>ISSN: 0030-4220</identifier><identifier>EISSN: 1878-2175</identifier><identifier>DOI: 10.1016/0030-4220(88)90237-X</identifier><identifier>PMID: 2845325</identifier><identifier>CODEN: OSOMAE</identifier><language>eng</language><publisher>Saint Louis, MO: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Dentistry ; Female ; Genes, Dominant ; Humans ; Hypophosphatemia, Familial - genetics ; Male ; Medical genetics ; Medical sciences ; Phenotype ; Tooth Abnormalities - etiology ; Tooth Diseases - etiology ; X Chromosome</subject><ispartof>Oral surgery, oral medicine, oral pathology, 1988-09, Vol.66 (3), p.310-314</ispartof><rights>1988</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-6bbd85966f343ca6793dacf4dfbca35a68f3f3cada840200e6f63e6b50a341913</citedby><cites>FETCH-LOGICAL-c387t-6bbd85966f343ca6793dacf4dfbca35a68f3f3cada840200e6f63e6b50a341913</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19550137$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2845325$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schwartz, S.</creatorcontrib><creatorcontrib>Scriver, C.R.</creatorcontrib><creatorcontrib>Reade, T.M.</creatorcontrib><creatorcontrib>Shields, E.D.</creatorcontrib><title>Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseases</title><title>Oral surgery, oral medicine, oral pathology</title><addtitle>Oral Surg Oral Med Oral Pathol</addtitle><description>Oral examinations were performed on 5 patients with hypophosphatemic bone disease (HBD) (2 males and 3 females), 14 patients with X-linked hypophosphatemia (XLH), and 4 affected XLH relatives (6 males and 12 females). The control subjects were the unaffected siblings and parents of the patients and unrelated healthy, gender- and age-matched subjects. Serum phosphorus values were the same by disease type and gender in patients with HBD and XLH. They shared certain dental abnormalities, in particular pulpal necrosis and large pulp spaces. However, only patients with XLH had Class III malocclusions and mild enamel defects, and males with XLH had more severe occlusal and enamel defects than females with XLH. Different dental phenotypes are further evidence that XLH and HBD are different diseases. The dental abnormalities were not prevented by treatment, instituted early in life, which raised serum phosphorus to the near normal range.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Dentistry</subject><subject>Female</subject><subject>Genes, Dominant</subject><subject>Humans</subject><subject>Hypophosphatemia, Familial - genetics</subject><subject>Male</subject><subject>Medical genetics</subject><subject>Medical sciences</subject><subject>Phenotype</subject><subject>Tooth Abnormalities - etiology</subject><subject>Tooth Diseases - etiology</subject><subject>X Chromosome</subject><issn>0030-4220</issn><issn>1878-2175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUGL1TAUhYMo43P0Hyhko-iimjZtmroQZHBUGJiNwtuF2-TGRtu0JunI-zf-VFPfcwQXbhLC-e654RxCHpfsZclK8Yoxzoq6qthzKV90rOJtsb9DdqVsZVGVbXOX7G6R--RBjF_zs60FPyNnlawbXjU78vM6wEit88b5L5E6TxdIDn2K9IdLA4U1zXGeMmPmyXnwiQ6HZV6GOS4DJJycpv3skRoXESJS8Ibui9H5b2j-ReE1vVxDGjBQvHEGvUaaspQPPFAIm4u1GPL6P37xIblnYYz46HSfk8-X7z5dfCiurt9_vHh7VWgu21SIvjey6YSwvOYaRNtxA9rWxvYaeANCWm6zYEDWrGIMhRUcRd8w4HXZlfycPDv6LmH-vmJManJR4ziCx3mNqpW1aLiUGayPoA5zjAGtWoKbIBxUydRWjNpSV1vqSkr1uxi1z2NPTv5rP6G5HTo1kfWnJx2ihtEG8NrFv95d07CSt5l7c-Qwh3HjMKio3ZakcQF1UmZ2___ILzBDrp0</recordid><startdate>19880901</startdate><enddate>19880901</enddate><creator>Schwartz, S.</creator><creator>Scriver, C.R.</creator><creator>Reade, T.M.</creator><creator>Shields, E.D.</creator><general>Elsevier Inc</general><general>Mosby</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19880901</creationdate><title>Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseases</title><author>Schwartz, S. ; Scriver, C.R. ; Reade, T.M. ; Shields, E.D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-6bbd85966f343ca6793dacf4dfbca35a68f3f3cada840200e6f63e6b50a341913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Dentistry</topic><topic>Female</topic><topic>Genes, Dominant</topic><topic>Humans</topic><topic>Hypophosphatemia, Familial - genetics</topic><topic>Male</topic><topic>Medical genetics</topic><topic>Medical sciences</topic><topic>Phenotype</topic><topic>Tooth Abnormalities - etiology</topic><topic>Tooth Diseases - etiology</topic><topic>X Chromosome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schwartz, S.</creatorcontrib><creatorcontrib>Scriver, C.R.</creatorcontrib><creatorcontrib>Reade, T.M.</creatorcontrib><creatorcontrib>Shields, E.D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Oral surgery, oral medicine, oral pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schwartz, S.</au><au>Scriver, C.R.</au><au>Reade, T.M.</au><au>Shields, E.D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseases</atitle><jtitle>Oral surgery, oral medicine, oral pathology</jtitle><addtitle>Oral Surg Oral Med Oral Pathol</addtitle><date>1988-09-01</date><risdate>1988</risdate><volume>66</volume><issue>3</issue><spage>310</spage><epage>314</epage><pages>310-314</pages><issn>0030-4220</issn><eissn>1878-2175</eissn><coden>OSOMAE</coden><abstract>Oral examinations were performed on 5 patients with hypophosphatemic bone disease (HBD) (2 males and 3 females), 14 patients with X-linked hypophosphatemia (XLH), and 4 affected XLH relatives (6 males and 12 females). The control subjects were the unaffected siblings and parents of the patients and unrelated healthy, gender- and age-matched subjects. Serum phosphorus values were the same by disease type and gender in patients with HBD and XLH. They shared certain dental abnormalities, in particular pulpal necrosis and large pulp spaces. However, only patients with XLH had Class III malocclusions and mild enamel defects, and males with XLH had more severe occlusal and enamel defects than females with XLH. Different dental phenotypes are further evidence that XLH and HBD are different diseases. The dental abnormalities were not prevented by treatment, instituted early in life, which raised serum phosphorus to the near normal range.</abstract><cop>Saint Louis, MO</cop><pub>Elsevier Inc</pub><pmid>2845325</pmid><doi>10.1016/0030-4220(88)90237-X</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0030-4220 |
| ispartof | Oral surgery, oral medicine, oral pathology, 1988-09, Vol.66 (3), p.310-314 |
| issn | 0030-4220 1878-2175 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78465388 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Biological and medical sciences Dentistry Female Genes, Dominant Humans Hypophosphatemia, Familial - genetics Male Medical genetics Medical sciences Phenotype Tooth Abnormalities - etiology Tooth Diseases - etiology X Chromosome |
| title | Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseases |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T05%3A07%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Oral%20findings%20in%20patients%20with%20autosomal%20dominant%20hypophosphatemic%20bone%20disease%20and%20X-linked%20hypophosphatemia:%20Further%20evidence%20that%20they%20are%20different%20diseases&rft.jtitle=Oral%20surgery,%20oral%20medicine,%20oral%20pathology&rft.au=Schwartz,%20S.&rft.date=1988-09-01&rft.volume=66&rft.issue=3&rft.spage=310&rft.epage=314&rft.pages=310-314&rft.issn=0030-4220&rft.eissn=1878-2175&rft.coden=OSOMAE&rft_id=info:doi/10.1016/0030-4220(88)90237-X&rft_dat=%3Cproquest_cross%3E78465388%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78465388&rft_id=info:pmid/2845325&rft_els_id=003042208890237X&rfr_iscdi=true |