Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research
Existing data suggests dramatic efficacy for all tested tricyclics in disorders involving spontaneous panic attacks; moderate efficacy for clomipramine but not other tricyclics in obsessive-compulsive patients; possible, but as yet not well established, tricyclic efficacy in generalized anxiety; and...
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Veröffentlicht in: | Journal of psychiatric research 1988, Vol.22, p.7-31 |
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container_title | Journal of psychiatric research |
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creator | Liebowitz, Michael R. Fyer, Abby J. Gorman, Jack M. Campeas, Raphael B. Sandberg, Diana P. Hollander, Eric Papp, Lazlo A. Klein, Donald F. |
description | Existing data suggests dramatic efficacy for all tested tricyclics in disorders involving spontaneous panic attacks; moderate efficacy for clomipramine but not other tricyclics in obsessive-compulsive patients; possible, but as yet not well established, tricyclic efficacy in generalized anxiety; and lack of efficacy in simple phobias. Further studies in all DSM-III Anxiety Disorders are both warranted and required to answer the nonological, pathophysiological and treatment questions raised by these findings. |
doi_str_mv | 10.1016/0022-3956(88)90067-2 |
format | Article |
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Further studies in all DSM-III Anxiety Disorders are both warranted and required to answer the nonological, pathophysiological and treatment questions raised by these findings.</description><subject>Adolescent</subject><subject>Antidepressive Agents, Tricyclic - therapeutic use</subject><subject>Anxiety Disorders - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Clomipramine - therapeutic use</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Obsessive-Compulsive Disorder - drug therapy</subject><subject>Panic - drug effects</subject><subject>Pharmacology. Drug treatments</subject><subject>Phobic Disorders - drug therapy</subject><subject>Psycholeptics: tranquillizer, neuroleptic</subject><subject>Psychology. Psychoanalysis. 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Drug treatments</topic><topic>Phobic Disorders - drug therapy</topic><topic>Psycholeptics: tranquillizer, neuroleptic</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liebowitz, Michael R.</creatorcontrib><creatorcontrib>Fyer, Abby J.</creatorcontrib><creatorcontrib>Gorman, Jack M.</creatorcontrib><creatorcontrib>Campeas, Raphael B.</creatorcontrib><creatorcontrib>Sandberg, Diana P.</creatorcontrib><creatorcontrib>Hollander, Eric</creatorcontrib><creatorcontrib>Papp, Lazlo A.</creatorcontrib><creatorcontrib>Klein, Donald F.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of psychiatric research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liebowitz, Michael R.</au><au>Fyer, Abby J.</au><au>Gorman, Jack M.</au><au>Campeas, Raphael B.</au><au>Sandberg, Diana P.</au><au>Hollander, Eric</au><au>Papp, Lazlo A.</au><au>Klein, Donald F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research</atitle><jtitle>Journal of psychiatric research</jtitle><addtitle>J Psychiatr Res</addtitle><date>1988</date><risdate>1988</risdate><volume>22</volume><spage>7</spage><epage>31</epage><pages>7-31</pages><issn>0022-3956</issn><eissn>1879-1379</eissn><coden>JPYRA3</coden><abstract>Existing data suggests dramatic efficacy for all tested tricyclics in disorders involving spontaneous panic attacks; moderate efficacy for clomipramine but not other tricyclics in obsessive-compulsive patients; possible, but as yet not well established, tricyclic efficacy in generalized anxiety; and lack of efficacy in simple phobias. 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subjects | Adolescent Antidepressive Agents, Tricyclic - therapeutic use Anxiety Disorders - drug therapy Biological and medical sciences Child Clomipramine - therapeutic use Humans Medical sciences Neuropharmacology Obsessive-Compulsive Disorder - drug therapy Panic - drug effects Pharmacology. Drug treatments Phobic Disorders - drug therapy Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology |
title | Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research |
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