Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research

Existing data suggests dramatic efficacy for all tested tricyclics in disorders involving spontaneous panic attacks; moderate efficacy for clomipramine but not other tricyclics in obsessive-compulsive patients; possible, but as yet not well established, tricyclic efficacy in generalized anxiety; and...

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Veröffentlicht in:Journal of psychiatric research 1988, Vol.22, p.7-31
Hauptverfasser: Liebowitz, Michael R., Fyer, Abby J., Gorman, Jack M., Campeas, Raphael B., Sandberg, Diana P., Hollander, Eric, Papp, Lazlo A., Klein, Donald F.
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container_end_page 31
container_issue
container_start_page 7
container_title Journal of psychiatric research
container_volume 22
creator Liebowitz, Michael R.
Fyer, Abby J.
Gorman, Jack M.
Campeas, Raphael B.
Sandberg, Diana P.
Hollander, Eric
Papp, Lazlo A.
Klein, Donald F.
description Existing data suggests dramatic efficacy for all tested tricyclics in disorders involving spontaneous panic attacks; moderate efficacy for clomipramine but not other tricyclics in obsessive-compulsive patients; possible, but as yet not well established, tricyclic efficacy in generalized anxiety; and lack of efficacy in simple phobias. Further studies in all DSM-III Anxiety Disorders are both warranted and required to answer the nonological, pathophysiological and treatment questions raised by these findings.
doi_str_mv 10.1016/0022-3956(88)90067-2
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Adolescent
Antidepressive Agents, Tricyclic - therapeutic use
Anxiety Disorders - drug therapy
Biological and medical sciences
Child
Clomipramine - therapeutic use
Humans
Medical sciences
Neuropharmacology
Obsessive-Compulsive Disorder - drug therapy
Panic - drug effects
Pharmacology. Drug treatments
Phobic Disorders - drug therapy
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
title Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research
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