Effect of citalopram, a selective serotonin reuptake inhibitor, on the acquisition of conditioned freezing

The present study examined the effects of the selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor citalopram on the acquisition of conditioned freezing, an index of anxiety. Acute treatment with citalopram (1–10 mg/kg) dose dependently prevented the acquisition of conditioned freezing...

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Veröffentlicht in:	European journal of pharmacology 1996-09, Vol.311 (1), p.1-6
Hauptverfasser:	Inoue, Takeshi, Hashimoto, Shinji, Tsuchiya, Kiyoshi, Izumi, Takeshi, Ohmori, Tetsuro, Koyama, Tsukasa
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT (5-hydroxytryptamine, serotonin) reuptake inhibitor, selective Adrenergic Uptake Inhibitors - pharmacology Animals Anxiety Behavior, Animal - drug effects Biological and medical sciences Citalopram Citalopram - pharmacology Conditioned fear stress Conditioning (Psychology) - drug effects Dopamine Uptake Inhibitors - pharmacology Dose-Response Relationship, Drug Electroshock Fear - drug effects Freezing behavior Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Piperazines - pharmacology Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Pyridines - pharmacology Rats Rats, Sprague-Dawley Serotonin Uptake Inhibitors - pharmacology Stress, Psychological - psychology
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