Rapid Preparation of Giant Unilamellar Vesicles

We report here a rapid evaporation method that produces in high yield giant unilamellar vesicles up to 50 $\mu $m in diameter. The vesicles are obtained after only 2 min and can be prepared from different phospholipids, including L-$\alpha $-phosphatidylcholine (lecithin), dipalmitoleoyl L-$\alpha $...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-10, Vol.93 (21), p.11443-11447
Hauptverfasser:	Moscho, Alexander, Orwar, Owe, Chiu, Daniel T., Modi, Biren P., Zare, Richard N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Borates Chemistry Drug Stability Enzymes Evaporation gamma-Glutamyltransferase - chemistry gamma-Glutamyltransferase - metabolism Indicators and Reagents Liposomes Liposomes - chemical synthesis Liposomes - chemistry Molecular Conformation Molecules Phosphates Phospholipids Phospholipids - chemical synthesis Phospholipids - chemistry Proteolipids Solvents Structure-Activity Relationship Unilamellar liposomes
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