Mouse ovarian tumor cells: An experimental model for progestin-mediated radiotherapy
Mouse ovarian tumor (MOT) cells have been grown in C3HeB/FeJ mice as an ascites and as a subcutaneous tumor and in cell culture as a suspension. These cells contain saturable, high‐affinity, specific progesterone receptors. Estrogen receptors were not detectable in these cells. MOT cells can be used...
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| Veröffentlicht in: | Journal of surgical oncology 1988-10, Vol.39 (2), p.96-100 |
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| container_end_page | 100 |
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| container_issue | 2 |
| container_start_page | 96 |
| container_title | Journal of surgical oncology |
| container_volume | 39 |
| creator | Blumenthal, Rosalyn D. McLaughlin, William H. Jordan, Jerold J. Cryan, Ellen V. Bloomer, William D. |
| description | Mouse ovarian tumor (MOT) cells have been grown in C3HeB/FeJ mice as an ascites and as a subcutaneous tumor and in cell culture as a suspension. These cells contain saturable, high‐affinity, specific progesterone receptors. Estrogen receptors were not detectable in these cells. MOT cells can be used as both an in vivo and an in vitro model for progestin‐mediated radiotherapy. |
| doi_str_mv | 10.1002/jso.2930390206 |
| format | Article |
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These cells contain saturable, high‐affinity, specific progesterone receptors. Estrogen receptors were not detectable in these cells. MOT cells can be used as both an in vivo and an in vitro model for progestin‐mediated radiotherapy.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930390206</identifier><identifier>PMID: 3172797</identifier><identifier>CODEN: JSONAU</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animal tumors. 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Surg. Oncol</addtitle><description>Mouse ovarian tumor (MOT) cells have been grown in C3HeB/FeJ mice as an ascites and as a subcutaneous tumor and in cell culture as a suspension. These cells contain saturable, high‐affinity, specific progesterone receptors. Estrogen receptors were not detectable in these cells. MOT cells can be used as both an in vivo and an in vitro model for progestin‐mediated radiotherapy.</description><subject>Animal tumors. Experimental tumors</subject><subject>Animals</subject><subject>ascites tumor</subject><subject>Biological and medical sciences</subject><subject>Disease Models, Animal</subject><subject>Experimental genital and mammary tumors</subject><subject>Female</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Inbred C3H</subject><subject>Ovarian Neoplasms - analysis</subject><subject>Ovarian Neoplasms - pathology</subject><subject>Ovarian Neoplasms - radiotherapy</subject><subject>progesterone binding</subject><subject>receptor-mediated radiotherapy</subject><subject>Receptors, Estrogen - analysis</subject><subject>Receptors, Progesterone - analysis</subject><subject>Tumor Cells, Cultured</subject><subject>Tumors</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPHDEUha2IiCwkLR3SFCjdbPyYscd0aAkvQYgSIkrrzvg6GOax2LPA_vsY7WoRVSoX9zvH5xxC9hidMkr5t_s4TLkWVGjKqfxAJoxqmWuqqy0ySQDPC6XpJ7IT4z2lVGtZbJNtwRRXWk3IzdWwiJgNTxA89Nm46IaQNdi28TA76jN8mWPwHfYjtFk3WGwzl4B5GP5iHH2fd2g9jGizANYP4x0GmC8_k48O2ohf1u8u-XPy_WZ2ll9en57Pji7zRkguc1HLQteyss66QjWsqhEldYVQdcNUyWtQ2jreSIfU8lJKywU4JpUsJUBJxS75uvJNeR4XKZDpfHwNDz2mWkZVRak04wmcrsAmDDEGdGaeWkFYGkbN64wmzWjeZkyC_bXzok4VN_h6t3Q_WN8hNtC6AH3j4wZLETkTVcL0Cnv2LS7_86m5-H39LkK-0vo44stGC-Eh2QtVmtsfp-aY_botpPxpTsQ_uPKbXw</recordid><startdate>198810</startdate><enddate>198810</enddate><creator>Blumenthal, Rosalyn D.</creator><creator>McLaughlin, William H.</creator><creator>Jordan, Jerold J.</creator><creator>Cryan, Ellen V.</creator><creator>Bloomer, William D.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198810</creationdate><title>Mouse ovarian tumor cells: An experimental model for progestin-mediated radiotherapy</title><author>Blumenthal, Rosalyn D. ; McLaughlin, William H. ; Jordan, Jerold J. ; Cryan, Ellen V. ; Bloomer, William D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3626-3b649b68dfdf47c18bee60f437bc1752ba79df2c6fe0d2566d23af167656aa503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Animal tumors. Experimental tumors</topic><topic>Animals</topic><topic>ascites tumor</topic><topic>Biological and medical sciences</topic><topic>Disease Models, Animal</topic><topic>Experimental genital and mammary tumors</topic><topic>Female</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Inbred C3H</topic><topic>Ovarian Neoplasms - analysis</topic><topic>Ovarian Neoplasms - pathology</topic><topic>Ovarian Neoplasms - radiotherapy</topic><topic>progesterone binding</topic><topic>receptor-mediated radiotherapy</topic><topic>Receptors, Estrogen - analysis</topic><topic>Receptors, Progesterone - analysis</topic><topic>Tumor Cells, Cultured</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blumenthal, Rosalyn D.</creatorcontrib><creatorcontrib>McLaughlin, William H.</creatorcontrib><creatorcontrib>Jordan, Jerold J.</creatorcontrib><creatorcontrib>Cryan, Ellen V.</creatorcontrib><creatorcontrib>Bloomer, William D.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blumenthal, Rosalyn D.</au><au>McLaughlin, William H.</au><au>Jordan, Jerold J.</au><au>Cryan, Ellen V.</au><au>Bloomer, William D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mouse ovarian tumor cells: An experimental model for progestin-mediated radiotherapy</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1988-10</date><risdate>1988</risdate><volume>39</volume><issue>2</issue><spage>96</spage><epage>100</epage><pages>96-100</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><coden>JSONAU</coden><abstract>Mouse ovarian tumor (MOT) cells have been grown in C3HeB/FeJ mice as an ascites and as a subcutaneous tumor and in cell culture as a suspension. These cells contain saturable, high‐affinity, specific progesterone receptors. Estrogen receptors were not detectable in these cells. MOT cells can be used as both an in vivo and an in vitro model for progestin‐mediated radiotherapy.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>3172797</pmid><doi>10.1002/jso.2930390206</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-4790 |
| ispartof | Journal of surgical oncology, 1988-10, Vol.39 (2), p.96-100 |
| issn | 0022-4790 1096-9098 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animal tumors. Experimental tumors Animals ascites tumor Biological and medical sciences Disease Models, Animal Experimental genital and mammary tumors Female Medical sciences Mice Mice, Inbred C3H Ovarian Neoplasms - analysis Ovarian Neoplasms - pathology Ovarian Neoplasms - radiotherapy progesterone binding receptor-mediated radiotherapy Receptors, Estrogen - analysis Receptors, Progesterone - analysis Tumor Cells, Cultured Tumors |
| title | Mouse ovarian tumor cells: An experimental model for progestin-mediated radiotherapy |
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